RHLD_GORGO
ID RHLD_GORGO Reviewed; 417 AA.
AC Q28427;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=RH-like protein ID;
DE AltName: Full=Rhesus-like protein ID;
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Bone marrow;
RX PubMed=7993375; DOI=10.1007/bf00554623;
RA Salvignol I., Blancher A., Calvas P., Clayton J., Socha W.W., Colin Y.,
RA Ruffie J.;
RT "Molecular genetics of chimpanzee Rh-related genes: their relationship with
RT the R-C-E-F blood group system, the chimpanzee counterpart of the human
RT rhesus system.";
RL Biochem. Genet. 32:201-221(1994).
CC -!- FUNCTION: May be part of an oligomeric complex which is likely to have
CC a transport or channel function in the erythrocyte membrane.
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh
CC subfamily. {ECO:0000305}.
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DR EMBL; L37053; AAA65627.1; -; mRNA.
DR PIR; I37076; I37076.
DR RefSeq; NP_001266526.1; NM_001279597.1.
DR AlphaFoldDB; Q28427; -.
DR SMR; Q28427; -.
DR STRING; 9593.ENSGGOP00000010669; -.
DR GeneID; 101141062; -.
DR KEGG; ggo:101141062; -.
DR CTD; 6007; -.
DR eggNOG; KOG3796; Eukaryota.
DR OrthoDB; 910733at2759; -.
DR Proteomes; UP000001519; Unplaced.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0097272; P:ammonium homeostasis; IBA:GO_Central.
DR GO; GO:0072488; P:ammonium transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.10.3430.10; -; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR InterPro; IPR002229; RhesusRHD.
DR Pfam; PF00909; Ammonium_transp; 1.
DR PRINTS; PR00342; RHESUSRHD.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..417
FT /note="RH-like protein ID"
FT /id="PRO_0000168192"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 417 AA; 44969 MW; CC21B312E62374C2 CRC64;
MSSKYPRSVR CCLPLCALTL EAALTLLFYF FTHYDASLED QKGLVASYQV GQDLTVMAAI
GFGFLTSSFR GHSWSSVAFN LFMLALGVQW AILLDGFLSQ FPPGKVVITL FSIRLATMSA
LSVLISAGAV LGYVNLVQLV VMVLVEVTAL GTMRMVISNI FNTDYHMNMM HIYVFAACFG
LSVAWCLPKP LAKGTEDKDQ TATIPSLSAM LGALFLWMFW PSFNSALLRS PIERKNAVFN
TYYAVAVSVV TAISVSSLAH PQGKINMTYM HNAVLAGGVA VATSCHLIPS PWLAMVLGLV
AGLISIGGAK CLPGCCNRVL GIHDSSVMHY NFSLLGLLGE IIYIVLLVLD TVGAGNGMVG
FQVLVSIGEL SLAIVIALTS GLLTGLLLNL KIWKAPHAAK YFDDQVFWKF PHLAVGF