ID   RHMR_ECOLI              Reviewed;         260 AA.
AC   P77732;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 154.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator RhmR;
GN   Name=rhmR; Synonyms=yfaX; OrderedLocusNames=b2248, JW2242;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA   Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA   Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA   Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA   Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT   "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT   genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT   its sequence features.";
RL   DNA Res. 4:91-113(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- INTERACTION:
CC       P77732; P23862: priC; NbExp=3; IntAct=EBI-549004, EBI-1117383;
CC   -!- MISCELLANEOUS: Part of the rhmRDTA operon involved in L-rhamnonate
CC       utilization.
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DR   EMBL; U00096; AAC75308.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA16072.1; -; Genomic_DNA.
DR   PIR; F64995; F64995.
DR   RefSeq; NP_416751.1; NC_000913.3.
DR   RefSeq; WP_000894185.1; NZ_LN832404.1.
DR   AlphaFoldDB; P77732; -.
DR   SMR; P77732; -.
DR   BioGRID; 4261223; 5.
DR   BioGRID; 849155; 2.
DR   DIP; DIP-11956N; -.
DR   IntAct; P77732; 4.
DR   STRING; 511145.b2248; -.
DR   PaxDb; P77732; -.
DR   PRIDE; P77732; -.
DR   EnsemblBacteria; AAC75308; AAC75308; b2248.
DR   EnsemblBacteria; BAA16072; BAA16072; BAA16072.
DR   GeneID; 944752; -.
DR   KEGG; ecj:JW2242; -.
DR   KEGG; eco:b2248; -.
DR   PATRIC; fig|511145.12.peg.2339; -.
DR   EchoBASE; EB3839; -.
DR   eggNOG; COG1414; Bacteria.
DR   HOGENOM; CLU_062618_6_0_6; -.
DR   InParanoid; P77732; -.
DR   OMA; HDRRRMP; -.
DR   PhylomeDB; P77732; -.
DR   BioCyc; EcoCyc:G7161-MON; -.
DR   PRO; PR:P77732; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..260
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   RhmR"
FT                   /id="PRO_0000201770"
FT   DOMAIN          7..67
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
FT   DOMAIN          82..251
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00394"
FT   DNA_BIND        28..47
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00393"
SQ   SEQUENCE   260 AA;  28904 MW;  27016904BD41553C CRC64;
     MLESSKVPAL TRAIDILNLI ARIGPCSAAT IIDTLGIPKS TAYLLLNELR RQRFLSLDHQ
     ENFCLWTRLV ELSGHALSKM DLRELARPRL TQLMDTTGLL CHLGIIDNGS AYYILKVESS
     ATISVRSHEG KSLSLYRSGI GKCLLAWQPA AVQQSIIEGL VWEQATPTTI THPQQLHEEL
     ARIRRQGWSY DNGEDYADVR CVAAPVFNAN NELTAAISVV GTRLQINEEY RDYLAGKAIA
     CARDISRLLG WKSPFDLQAS