ID   RHN2P_HUMAN             Reviewed;         583 AA.
AC   A8MT19;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Putative rhophilin-2-like protein RHPN2P1;
DE   AltName: Full=Rhophilin-2 pseudogene 1;
GN   Name=RHPN2P1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R., Fahey J.,
RA   Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G., Johnson E.,
RA   Jones C., Kamat A., Kaur A., Locke D.P., Madan A., Munson G., Jaffe D.B.,
RA   Lui A., Macdonald P., Mauceli E., Naylor J.W., Nesbitt R., Nicol R.,
RA   O'Leary S.B., Ratcliffe A., Rounsley S., She X., Sneddon K.M.B.,
RA   Stewart S., Sougnez C., Stone S.M., Topham K., Vincent D., Wang S.,
RA   Zimmer A.R., Birren B.W., Hood L., Lander E.S., Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human chromosome
RT   15.";
RL   Nature 440:671-675(2006).
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AC126603; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A8MT19; -.
DR   SMR; A8MT19; -.
DR   BioMuta; HGNC:37708; -.
DR   EPD; A8MT19; -.
DR   jPOST; A8MT19; -.
DR   MassIVE; A8MT19; -.
DR   MaxQB; A8MT19; -.
DR   PeptideAtlas; A8MT19; -.
DR   PRIDE; A8MT19; -.
DR   GeneCards; RHPN2P1; -.
DR   HGNC; HGNC:37708; RHPN2P1.
DR   neXtProt; NX_A8MT19; -.
DR   InParanoid; A8MT19; -.
DR   PhylomeDB; A8MT19; -.
DR   SignaLink; A8MT19; -.
DR   ChiTaRS; RHPN2P1; human.
DR   Pharos; A8MT19; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; A8MT19; protein.
DR   GO; GO:0051497; P:negative regulation of stress fiber assembly; IBA:GO_Central.
DR   Gene3D; 1.25.40.280; -; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR004328; BRO1_dom.
DR   InterPro; IPR038499; BRO1_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   Pfam; PF03097; BRO1; 1.
DR   SMART; SM01041; BRO1; 1.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   PROSITE; PS51180; BRO1; 1.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..583
FT                   /note="Putative rhophilin-2-like protein RHPN2P1"
FT                   /id="PRO_0000340665"
FT   DOMAIN          26..375
FT                   /note="BRO1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00526"
FT   DOMAIN          412..490
FT                   /note="PDZ"
SQ   SEQUENCE   583 AA;  65945 MW;  1F4876E1565143E7 CRC64;
     MLKEELEGLN ISVGIYQNTE EAFTVPLIPL GLKETKDIDF SVILKDFILE HYSEDGYLYE
     DEITDLMDPR QACRTPSRDE ARVELLMTYF IQLGFAWIRF KKYNTSPRIF FYRYDSLNGV
     LVSQQNLLLE KASVLFNTGA LYTQIGTWRY WQMQAGLQSA IDAFQRAAGV LNYLKETFTH
     TPSYDMSPAM LSVLVKMMLT QAQESVFEKI SLPGIRNEFF MLVKVAQEAA KVGEVYQQLH
     AAMSQALVKE NIPYSWASLA CVKAHHYTAL AHYFTAILLI DHQVKPGMDL DHQEKCLSQL
     YDHMPEGLTP LATLKNDQQR RQLGKSHLHR AMAHHEESVR EASLCKKLRS IEVLQKVLCA
     AQERSRLTYA QHQEDDDLLN LIHAPSVVAK TEQEPKGPLS VFLANKQWMP PRSNRFTAEE
     GDLGFTLRGN APVEVHFLDP YCSALVAGAR GGDYIVSIQL VDCKWLTVSE VMKLLKSFGE
     DEIEMKVVSL LDSTSSMHNK SATYSVGMQK TYSMICLAID DDNKTDKTQK ISKKLSFLSW
     GTNKNRQKSA STLCLPSVGA ARPQVKKKLP SPFSLLNSDS SSY