ID   RHO_ACIFI               Reviewed;          58 AA.
AC   P52158;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Transcription termination factor Rho;
DE            EC=3.6.4.-;
DE   AltName: Full=ATP-dependent helicase Rho;
DE   Flags: Fragment;
GN   Name=rho;
OS   Acidithiobacillus ferridurans.
OC   Bacteria; Proteobacteria; Acidithiobacillia; Acidithiobacillales;
OC   Acidithiobacillaceae; Acidithiobacillus.
OX   NCBI_TaxID=1232575;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33020 / DSM 29468 / JCM 18981 / 11Fe;
RX   PubMed=7496529; DOI=10.1099/13500872-141-9-2175;
RA   Powles R.E., Deane S.M., Rawlings D.E.;
RT   "Molecular genetic analysis of a thioredoxin gene from Thiobacillus
RT   ferrooxidans.";
RL   Microbiology 141:2175-2181(1995).
CC   -!- FUNCTION: Facilitates transcription termination by a mechanism that
CC       involves Rho binding to the nascent RNA, activation of Rho's RNA-
CC       dependent ATPase activity, and release of the mRNA from the DNA
CC       template. {ECO:0000250}.
CC   -!- SUBUNIT: Homohexamer. The homohexamer assembles into an open ring
CC       structure (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Rho family. {ECO:0000305}.
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DR   EMBL; U20361; AAA88940.1; -; Genomic_DNA.
DR   AlphaFoldDB; P52158; -.
DR   SMR; P52158; -.
DR   STRING; 380394.Lferr_0807; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006353; P:DNA-templated transcription, termination; IEA:UniProtKB-KW.
DR   InterPro; IPR011112; Rho_N.
DR   InterPro; IPR036269; Rho_N_sf.
DR   Pfam; PF07498; Rho_N; 1.
DR   SMART; SM00959; Rho_N; 1.
DR   SUPFAM; SSF68912; SSF68912; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; RNA-binding;
KW   Transcription; Transcription regulation; Transcription termination.
FT   CHAIN           1..>58
FT                   /note="Transcription termination factor Rho"
FT                   /id="PRO_0000188981"
FT   NON_TER         58
SQ   SEQUENCE   58 AA;  6436 MW;  5F11D1CD932454EB CRC64;
     MNLTDLKRKT AADLAVICQD MGLEGTARQK KQEIIFNILN ARAQCDAIYG EGVLEILQ