ID   RHSA_ECOLI              Reviewed;        1377 AA.
AC   P16916; Q2M7Q6;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   03-AUG-2022, entry version 154.
DE   RecName: Full=Protein RhsA;
GN   Name=rhsA; OrderedLocusNames=b3593, JW3566;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2403547; DOI=10.1128/jb.172.1.446-456.1990;
RA   Feulner G., Gray J.A., Kirschman J.A., Lehner A.F., Sadosky A.B.,
RA   Vlazny D.A., Zhang J., Zhao S., Hill C.W.;
RT   "Structure of the rhsA locus from Escherichia coli K-12 and comparison of
RT   rhsA with other members of the rhs multigene family.";
RL   J. Bacteriol. 172:446-456(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   REVIEW.
RX   PubMed=7934896; DOI=10.1111/j.1365-2958.1994.tb01074.x;
RA   Hill C.W., Sandt C.H., Vlazny D.A.;
RT   "Rhs elements of Escherichia coli: a family of genetic composites each
RT   encoding a large mosaic protein.";
RL   Mol. Microbiol. 12:865-871(1994).
CC   -!- FUNCTION: Rhs elements have a nonessential function. They may play an
CC       important role in the natural ecology of the cell.
CC   -!- DOMAIN: Each rhs appears to consist of a highly conserved 141 kDa amino
CC       fragment followed by a highly divergent C-terminus.
CC   -!- SIMILARITY: Belongs to the RHS family. {ECO:0000305}.
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DR   EMBL; L19044; AAC95065.1; -; Genomic_DNA.
DR   EMBL; U00039; AAB18570.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76617.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77700.1; -; Genomic_DNA.
DR   PIR; C65159; C65159.
DR   RefSeq; NP_418050.1; NC_000913.3.
DR   RefSeq; WP_000015300.1; NZ_LN832404.1.
DR   AlphaFoldDB; P16916; -.
DR   SMR; P16916; -.
DR   BioGRID; 4262562; 134.
DR   DIP; DIP-10699N; -.
DR   IntAct; P16916; 27.
DR   STRING; 511145.b3593; -.
DR   PaxDb; P16916; -.
DR   PRIDE; P16916; -.
DR   EnsemblBacteria; AAC76617; AAC76617; b3593.
DR   EnsemblBacteria; BAE77700; BAE77700; BAE77700.
DR   GeneID; 948120; -.
DR   KEGG; ecj:JW3566; -.
DR   KEGG; eco:b3593; -.
DR   PATRIC; fig|511145.12.peg.3710; -.
DR   EchoBASE; EB0839; -.
DR   eggNOG; COG3209; Bacteria.
DR   HOGENOM; CLU_001218_0_1_6; -.
DR   InParanoid; P16916; -.
DR   OMA; CEDIANS; -.
DR   PhylomeDB; P16916; -.
DR   BioCyc; EcoCyc:EG10846-MON; -.
DR   PRO; PR:P16916; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   InterPro; IPR045351; DUF6531.
DR   InterPro; IPR028947; Ntox34.
DR   InterPro; IPR001826; RHS.
DR   InterPro; IPR022385; Rhs_assc_core.
DR   InterPro; IPR031325; RHS_repeat.
DR   InterPro; IPR006530; YD.
DR   Pfam; PF20148; DUF6531; 1.
DR   Pfam; PF15606; Ntox34; 1.
DR   Pfam; PF03527; RHS; 1.
DR   Pfam; PF05593; RHS_repeat; 7.
DR   PRINTS; PR00394; RHSPROTEIN.
DR   TIGRFAMs; TIGR03696; Rhs_assc_core; 1.
DR   TIGRFAMs; TIGR01643; YD_repeat_2x; 5.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat.
FT   CHAIN           1..1377
FT                   /note="Protein RhsA"
FT                   /id="PRO_0000022225"
FT   REPEAT          330..352
FT                   /note="1"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          353..374
FT                   /note="2"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          375..417
FT                   /note="3"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          418..438
FT                   /note="4"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          439..460
FT                   /note="5"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          461..481
FT                   /note="6"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          482..502
FT                   /note="7"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          503..525
FT                   /note="8"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          526..546
FT                   /note="9"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          547..567
FT                   /note="10"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          568..588
FT                   /note="11"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          589..609
FT                   /note="12"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          610..629
FT                   /note="13"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          630..650
FT                   /note="14"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          651..671
FT                   /note="15"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          672..691
FT                   /note="16"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          692..711
FT                   /note="17"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          712..734
FT                   /note="18"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          735..758
FT                   /note="19"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          808..828
FT                   /note="20"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          829..850
FT                   /note="21"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          851..871
FT                   /note="22"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          872..894
FT                   /note="23"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          895..930
FT                   /note="24"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          931..959
FT                   /note="25"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          960..984
FT                   /note="26"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          985..1019
FT                   /note="27"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REPEAT          1162..1186
FT                   /note="28"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REGION          330..1186
FT                   /note="28 X approximate tandem repeats"
FT                   /evidence="ECO:0000305|PubMed:2403547"
FT   REGION          1356..1377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1377 AA;  156321 MW;  21ACA989E74200FE CRC64;
     MSGKPAARQG DMTQYGGSIV QGSAGVRIGA PTGVACSVCP GGVTSGHPVN PLLGAKVLPG
     ETDIALPGPL PFILSRTYSS YRTKTPAPVG SLGPGWKMPA DIRLQLRDNT LILSDNGGRS
     LYFEHLFPGE DGYSRSESLW LVRGGVAKLD EGHRLAALWQ ALPEELRLSP HRYLATNSPQ
     GPWWLLGWCE RVPEADEVLP APLPPYRVLT GLVDRFGRTQ TFHREAAGEF SGEITGVTDG
     AWRHFRLVLT TQAQRAEEAR QQAISGGTEP SAFPDTLPGY TEYGRDNGIR LSAVWLTHDP
     EYPENLPAAP LVRYGWTPRG ELAVVYDRSG KQVRSFTYDD KYRGRMVAHR HTGRPEIRYR
     YDSDGRVTEQ LNPAGLSYTY QYEKDRITIT DSLDRREVLH TQGEAGLKRV VKKEHADGSV
     TQSQFDAVGR LRAQTDAAGR TTEYSPDVVT GLITRITTPD GRASAFYYNH HNQLTSATGP
     DGLELRREYD ELGRLIQETA PDGDITRYRY DNPHSDLPCA TEDATGSRKT MTWSRYGQLL
     SFTDCSGYVT RYDHDRFGQM TAVHREEGLS QYRAYDSRGQ LIAVKDTQGH ETRYEYNIAG
     DLTAVIAPDG SRNGTQYDAW GKAVRTTQGG LTRSMEYDAA GRVIRLTSEN GSHTTFRYDV
     LDRLIQETGF DGRTQRYHHD LTGKLIRSED EGLVTHWHYD EADRLTHRTV KGETAERWQY
     DERGWLTDIS HISEGHRVAV HYRYDEKGRL TGERQTVHHP QTEALLWQHE TRHAYNAQGL
     ANRCIPDSLP AVEWLTYGSG YLAGMKLGDT PLVEYTRDRL HRETLRSFGR YELTTAYTPA
     GQLQSQHLNS LLSDRDYTWN DNGELIRISS PRQTRSYSYS TTGRLTGVHT TAANLDIRIP
     YATDPAGNRL PDPELHPDST LSMWPDNRIA RDAHYLYRYD RHGRLTEKTD LIPEGVIRTD
     DERTHRYHYD SQHRLVHYTR TQYEEPLVES RYLYDPLGRR VAKRVWRRER DLTGWMSLSR
     KPQVTWYGWD GDRLTTIQND RTRIQTIYQP GSFTPLIRVE TATGELAKTQ RRSLADALQQ
     SGGEDGGSVV FPPVLVQMLD RLESEILADR VSEESRRWLA SCGLTVEQMQ NQMDPVYTPA
     RKIHLYHCDH RGLPLALISK EGTTEWCAEY DEWGNLLNEE NPHQLQQLIR LPGQQYDEES
     GLYYNRHRYY DPLQGRYITQ DPIGLKGGWN FYQYPLNPVT NTDPLGLEVF PRPFPLPIPW
     PKSPAQQQAD DNAAKALTKW WNDTASQRIF DSLILNNPGL ALDITMIASR GNVADTGITD
     RVNDIINDRF WSDGKKPDRC DVLQELIDCG DISAKDAKST QKAWNCRHSR QSNDKKR