RHSC_ECOLI
ID RHSC_ECOLI Reviewed; 1397 AA.
AC P16918; P77194;
DT 01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 4.
DT 03-AUG-2022, entry version 163.
DE RecName: Full=Protein RhsC;
GN Name=rhsC; OrderedLocusNames=b0700, JW0689;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=8387990; DOI=10.1128/jb.175.10.2799-2808.1993;
RA Zhao S., Sandt C.H., Feulner G., Vlazny D.A., Gray J.A., Hill C.W.;
RT "Rhs elements of Escherichia coli K-12: complex composites of shared and
RT unique components that have different evolutionary histories.";
RL J. Bacteriol. 175:2799-2808(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-100.
RC STRAIN=K12;
RX PubMed=2644231; DOI=10.1128/jb.171.2.636-642.1989;
RA Sadosky A.B., Davidson A., Lin R.J., Hill C.W.;
RT "rhs gene family of Escherichia coli K-12.";
RL J. Bacteriol. 171:636-642(1989).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1221-1397.
RC STRAIN=K12;
RX PubMed=2403547; DOI=10.1128/jb.172.1.446-456.1990;
RA Feulner G., Gray J.A., Kirschman J.A., Lehner A.F., Sadosky A.B.,
RA Vlazny D.A., Zhang J., Zhao S., Hill C.W.;
RT "Structure of the rhsA locus from Escherichia coli K-12 and comparison of
RT rhsA with other members of the rhs multigene family.";
RL J. Bacteriol. 172:446-456(1990).
RN [7]
RP REVIEW.
RX PubMed=7934896; DOI=10.1111/j.1365-2958.1994.tb01074.x;
RA Hill C.W., Sandt C.H., Vlazny D.A.;
RT "Rhs elements of Escherichia coli: a family of genetic composites each
RT encoding a large mosaic protein.";
RL Mol. Microbiol. 12:865-871(1994).
CC -!- FUNCTION: Rhs elements have a nonessential function. They may play an
CC important role in the natural ecology of the cell.
CC -!- INTERACTION:
CC P16918; P23869: ppiB; NbExp=6; IntAct=EBI-546818, EBI-555935;
CC -!- DOMAIN: Each rhs appears to consist of a highly conserved 141 kDa amino
CC fragment followed by a highly divergent C-terminus.
CC -!- SIMILARITY: Belongs to the RHS family. {ECO:0000305}.
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DR EMBL; L19044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U00096; AAC73794.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35359.1; -; Genomic_DNA.
DR EMBL; L02373; AAC63072.1; -; Genomic_DNA.
DR PIR; C64805; C64805.
DR PIR; E65145; E65145.
DR RefSeq; NP_415229.1; NC_000913.3.
DR RefSeq; WP_000015200.1; NZ_LN832404.1.
DR AlphaFoldDB; P16918; -.
DR SMR; P16918; -.
DR BioGRID; 4263131; 1.
DR BioGRID; 849683; 2.
DR DIP; DIP-10701N; -.
DR IntAct; P16918; 33.
DR STRING; 511145.b0700; -.
DR PaxDb; P16918; -.
DR PRIDE; P16918; -.
DR EnsemblBacteria; AAC73794; AAC73794; b0700.
DR EnsemblBacteria; BAA35359; BAA35359; BAA35359.
DR GeneID; 945306; -.
DR KEGG; ecj:JW0689; -.
DR KEGG; eco:b0700; -.
DR PATRIC; fig|511145.12.peg.731; -.
DR EchoBASE; EB0841; -.
DR eggNOG; COG3209; Bacteria.
DR HOGENOM; CLU_001218_0_1_6; -.
DR InParanoid; P16918; -.
DR OMA; ATHQKYY; -.
DR PhylomeDB; P16918; -.
DR BioCyc; EcoCyc:EG10848-MON; -.
DR PRO; PR:P16918; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR InterPro; IPR045351; DUF6531.
DR InterPro; IPR001826; RHS.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR031325; RHS_repeat.
DR InterPro; IPR006530; YD.
DR Pfam; PF20148; DUF6531; 1.
DR Pfam; PF03527; RHS; 1.
DR Pfam; PF05593; RHS_repeat; 7.
DR PRINTS; PR00394; RHSPROTEIN.
DR TIGRFAMs; TIGR03696; Rhs_assc_core; 1.
DR TIGRFAMs; TIGR01643; YD_repeat_2x; 6.
PE 1: Evidence at protein level;
KW Reference proteome; Repeat.
FT CHAIN 1..1397
FT /note="Protein RhsC"
FT /id="PRO_0000022227"
FT REPEAT 330..352
FT /note="1"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 353..374
FT /note="2"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 375..417
FT /note="3"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 418..438
FT /note="4"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 439..460
FT /note="5"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 461..481
FT /note="6"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 482..502
FT /note="7"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 503..525
FT /note="8"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 526..546
FT /note="9"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 547..567
FT /note="10"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 568..588
FT /note="11"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 589..609
FT /note="12"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 610..629
FT /note="13"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 630..650
FT /note="14"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 651..671
FT /note="15"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 672..691
FT /note="16"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 692..711
FT /note="17"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 712..734
FT /note="18"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 735..758
FT /note="19"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 808..828
FT /note="20"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 829..850
FT /note="21"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 851..871
FT /note="22"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 872..894
FT /note="23"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 895..930
FT /note="24"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 931..959
FT /note="25"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 960..984
FT /note="26"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 985..1019
FT /note="27"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REPEAT 1162..1186
FT /note="28"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REGION 330..1186
FT /note="28 X approximate tandem repeats"
FT /evidence="ECO:0000305|PubMed:8387990"
FT REGION 1292..1312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1397 AA; 157776 MW; 0AC56AEE77E15C30 CRC64;
MSGKPAARQG DMTQYGGSIV QGSAGVRIGA PTGVACSVCP GGVTSGHPVN PLLGAKVLPG
ETDIALPGPL PFILSRTYSS YRTKTPAPVG SLGPGWKMPA DIRLQLRDNT LILSDNGGRS
LYFEHLFPGE DGYSRSESLW LVRGGVAKLD EGHRLAALWQ ALPEELRLSP HRYLATNSPQ
GPWWLLGWCE RVPEADEVLP APLPPYRVLT GLVDRFGRTQ TFHREAAGEF SGEITGVTDG
AGRHFRLVLT TQAQRAEEAR QQAISGGTEP SAFPDTLPGY TEYGRDNGIR LSAVWLTHDP
EYPENLPAAP LVRYGWTPRG ELAAVYDRSN TQVRSFTYDD KYRGRMVAHR HTGRPEICYR
YDSDGRVTEQ LNPAGLSYTY QYEKDRITIT DSLNRREVLH TQGEGGLKRV VKKEHADGSV
TQSQFDAVGR LRAQTDAAGR TTEYSPDVVT GLITRITTPD GRASAFYYNH HSQLTSATGP
DGLEIRREYD EWGRLIQETA PDGDITRYRY DNPHSDLPCA TEDATGSRKT MTWSRYGQLL
SFTDCSGYVT RYDHDRFGQV TAVHREEGLS QYRAYDSRGQ LIAVKDTQGH ETRYEYNAAG
DLTTVIAPDG SRNGTQYDAW GKAICTTQGG LTRSMEYDAA GRVIRLTSEN GSHTTFRYDV
LDRLIQETGF DGRTQRYHHD LTGKLIRSED EGLVTHWHYD EADRLTHRTV NGETAERWQY
DERGWLTDIS HISEGHRVTV HYGYDSKGRL ASEHLTVHHP QTNELLWQHE TRHAYNAQGL
ANRCIPDSLP AVEWLTYGSG WLSGMKLGDT PLVEYTRDRL HRETLRSFGR YELTTAYTPA
GQLQSQHLNS LLSDRDYTWN DNGELIRISS PRQTRSYSYS TTGRLTGVHT TAANLDIRIP
YTTDPAGNRL PDPELHPDSA LSMWPDNRIA RDAHYLYRYD RHGRLTEKTD LIPEGVIRTD
DERTHRYHYD SQHRLVHYTR TQYAEPLVES RYLYDPLGRR VAKRVWRRER DLTGWMSLSR
KPQVTWYGWD GDRLTTIQND RTRIQTIYQP GSFTPLIRVE TATGELAKTQ RRSLADTLQQ
SGGEDGGSVV FPPVLVQMLD RLESEILADR VSEESRRWLA SCGLTVAQMQ SQMDPVYTPA
RKIHLYHCDH RGLPLALIST EGTTAWYAEY DEWGNLLNEE NPHQLQQLIR LPGQQYDEES
GLYYNRHRYY DPLQGRYITQ DPIGLKGGWN FYQYPLNPIS NIDPLGLETL KCIKPLHSMG
GTGERSGPDI WGNPFYHQYL CVPDGKGDYT CGGQDQRGES KGDGLWGPGK ASNDTKEAAG
RCDLVETDNS CVENCLKGKF KEVRPRYSVL PDIFTPINLG LFKNCQDWSN DSLETCKMKC
SGNNIGRFIR FVFTGVM
