RHSIC_DICD3
ID RHSIC_DICD3 Reviewed; 140 AA.
AC E0SGL8;
DT 16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT 02-NOV-2010, sequence version 1.
DT 03-AUG-2022, entry version 31.
DE RecName: Full=Immunity protein RhsIC;
GN Name=rhsIC; OrderedLocusNames=Dda3937_00826;
OS Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Dickeya.
OX NCBI_TaxID=198628;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3937;
RX PubMed=21217001; DOI=10.1128/jb.01513-10;
RA Glasner J.D., Yang C.H., Reverchon S., Hugouvieux-Cotte-Pattat N.,
RA Condemine G., Bohin J.P., Van Gijsegem F., Yang S., Franza T., Expert D.,
RA Plunkett G. III, San Francisco M.J., Charkowski A.O., Py B., Bell K.,
RA Rauscher L., Rodriguez-Palenzuela P., Toussaint A., Holeva M.C., He S.Y.,
RA Douet V., Boccara M., Blanco C., Toth I., Anderson B.D., Biehl B.S.,
RA Mau B., Flynn S.M., Barras F., Lindeberg M., Birch P.R., Tsuyumu S.,
RA Shi X., Hibbing M., Yap M.N., Carpentier M., Dassa E., Umehara M.,
RA Kim J.F., Rusch M., Soni P., Mayhew G.F., Fouts D.E., Gill S.R.,
RA Blattner F.R., Keen N.T., Perna N.T.;
RT "Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937.";
RL J. Bacteriol. 193:2076-2077(2011).
RN [2]
RP FUNCTION AS AN IMMUNITY PROTEIN, EXPRESSION IN E.COLI, AND DISRUPTION
RP PHENOTYPE.
RC STRAIN=3937;
RX PubMed=23572593; DOI=10.1073/pnas.1300627110;
RA Koskiniemi S., Lamoureux J.G., Nikolakakis K.C., t'Kint de Roodenbeke C.,
RA Kaplan M.D., Low D.A., Hayes C.S.;
RT "Rhs proteins from diverse bacteria mediate intercellular competition.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:7032-7037(2013).
CC -!- FUNCTION: Putative immunity protein component of a toxin-immunity
CC protein module, which may function as a cellular contact-dependent
CC growth inhibition (CDI) system. Blocks the toxic effects of expression
CC of the C-terminus (residues 1519-1658) of cognate toxin RhsC in E.coli.
CC {ECO:0000269|PubMed:23572593}.
CC -!- DISRUPTION PHENOTYPE: A double rhsC-rhsIC deletion is not outcompeted
CC by wild-type cells. {ECO:0000269|PubMed:23572593}.
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DR EMBL; CP002038; ADM97667.1; -; Genomic_DNA.
DR RefSeq; WP_013317128.1; NC_014500.1.
DR AlphaFoldDB; E0SGL8; -.
DR STRING; 198628.Dda3937_00826; -.
DR EnsemblBacteria; ADM97667; ADM97667; Dda3937_00826.
DR GeneID; 30316613; -.
DR KEGG; ddd:Dda3937_00826; -.
DR eggNOG; ENOG502ZJWN; Bacteria.
DR HOGENOM; CLU_1822431_0_0_6; -.
DR OrthoDB; 2010846at2; -.
DR BioCyc; DDAD198628:DDA3937_RS22035-MON; -.
DR Proteomes; UP000006859; Chromosome.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..140
FT /note="Immunity protein RhsIC"
FT /id="PRO_0000423981"
SQ SEQUENCE 140 AA; 16525 MW; 7B36A674D8BD061E CRC64;
MTFQTLSSEN NELLTIASES FLKRWAFSEQ RLTVDLMTSD DDELTVYIET DLVQSSPIYL
NEDLNICRLS IQDMHEILAV QHGYYVPPSR FGDLMKYSSE CYSFFYGRKS DFKYLASFIG
YEKYIACPIR FLEDISWRIR