ID   RHTC_SALTY              Reviewed;         206 AA.
AC   Q9L6N7;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Threonine efflux protein;
GN   Name=rhtC; OrderedLocusNames=STM3959; ORFNames=STMD1.31;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Conducts the efflux of threonine. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Rht family. {ECO:0000305}.
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DR   EMBL; AF233324; AAF33433.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL22803.1; -; Genomic_DNA.
DR   RefSeq; NP_462844.1; NC_003197.2.
DR   RefSeq; WP_000980080.1; NC_003197.2.
DR   AlphaFoldDB; Q9L6N7; -.
DR   STRING; 99287.STM3959; -.
DR   PaxDb; Q9L6N7; -.
DR   EnsemblBacteria; AAL22803; AAL22803; STM3959.
DR   GeneID; 1255485; -.
DR   KEGG; stm:STM3959; -.
DR   PATRIC; fig|99287.12.peg.4177; -.
DR   HOGENOM; CLU_079569_0_1_6; -.
DR   OMA; MAWLHNI; -.
DR   PhylomeDB; Q9L6N7; -.
DR   BioCyc; SENT99287:STM3959-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR   InterPro; IPR004778; Homoserine/Threonine_efflux.
DR   InterPro; IPR001123; LeuE-type.
DR   PANTHER; PTHR30086; PTHR30086; 1.
DR   Pfam; PF01810; LysE; 1.
DR   PIRSF; PIRSF006324; LeuE; 1.
DR   TIGRFAMs; TIGR00949; 2A76; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..206
FT                   /note="Threonine efflux protein"
FT                   /id="PRO_0000094739"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..43
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        65..66
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        88..149
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        174..206
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   206 AA;  22498 MW;  080477853FC2733F CRC64;
     MMMLFFTVAM VHIVALMSPG PDFFFVSQTA VSRSRKEAMM GVLGITCGVM VWAGVALLGL
     HLIIEKMAWL HTIIMVGGGL YLCWMGYQML RGALKKQDAA ASSPHIELAQ SGRSFLKGLL
     TNLSNPKAII YFGSVFSLFV GDNVGAAARW GIFALITLET LAWFTVVASL FALPKMRRGY
     QRLAKWIDGF AGALFAGFGI HLIISR