ID   RIAD1_HUMAN             Reviewed;          92 AA.
AC   A6NNX1;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=RIIa domain-containing protein 1;
GN   Name=RIIAD1; Synonyms=C1orf230;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA   Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA   Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA   Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA   Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA   Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA   Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA   Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA   Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA   Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA   Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA   Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA   Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA   Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA   McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA   Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA   Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA   Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA   Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA   Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA   White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA   Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA   Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA   Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AL589765; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471121; EAW53418.1; -; Genomic_DNA.
DR   CCDS; CCDS53368.1; -.
DR   RefSeq; NP_001138428.1; NM_001144956.1.
DR   AlphaFoldDB; A6NNX1; -.
DR   SMR; A6NNX1; -.
DR   BioGRID; 129887; 5.
DR   STRING; 9606.ENSP00000419249; -.
DR   PhosphoSitePlus; A6NNX1; -.
DR   BioMuta; RIIAD1; -.
DR   MassIVE; A6NNX1; -.
DR   PaxDb; A6NNX1; -.
DR   PeptideAtlas; A6NNX1; -.
DR   PRIDE; A6NNX1; -.
DR   ProteomicsDB; 1645; -.
DR   Antibodypedia; 50162; 17 antibodies from 9 providers.
DR   DNASU; 284485; -.
DR   Ensembl; ENST00000479191.2; ENSP00000419249.1; ENSG00000178796.13.
DR   GeneID; 284485; -.
DR   KEGG; hsa:284485; -.
DR   MANE-Select; ENST00000479191.2; ENSP00000419249.1; NM_001144956.3; NP_001138428.1.
DR   UCSC; uc010pdj.2; human.
DR   CTD; 284485; -.
DR   GeneCards; RIIAD1; -.
DR   HGNC; HGNC:26686; RIIAD1.
DR   HPA; ENSG00000178796; Group enriched (fallopian tube, pituitary gland, testis).
DR   neXtProt; NX_A6NNX1; -.
DR   OpenTargets; ENSG00000178796; -.
DR   PharmGKB; PA165750490; -.
DR   VEuPathDB; HostDB:ENSG00000178796; -.
DR   eggNOG; ENOG502S8ZF; Eukaryota.
DR   GeneTree; ENSGT00390000003062; -.
DR   HOGENOM; CLU_144881_1_1_1; -.
DR   InParanoid; A6NNX1; -.
DR   OMA; MAVPNHN; -.
DR   OrthoDB; 1599414at2759; -.
DR   PhylomeDB; A6NNX1; -.
DR   TreeFam; TF328360; -.
DR   PathwayCommons; A6NNX1; -.
DR   SignaLink; A6NNX1; -.
DR   BioGRID-ORCS; 284485; 12 hits in 1058 CRISPR screens.
DR   GenomeRNAi; 284485; -.
DR   Pharos; A6NNX1; Tdark.
DR   PRO; PR:A6NNX1; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   RNAct; A6NNX1; protein.
DR   Bgee; ENSG00000178796; Expressed in oocyte and 128 other tissues.
DR   ExpressionAtlas; A6NNX1; baseline and differential.
DR   Genevisible; A6NNX1; HS.
DR   InterPro; IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
DR   Pfam; PF02197; RIIa; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..92
FT                   /note="RIIa domain-containing protein 1"
FT                   /id="PRO_0000342467"
FT   DOMAIN          43..77
FT                   /note="RIIa"
SQ   SEQUENCE   92 AA;  10810 MW;  7E9EFB0E53A061E6 CRC64;
     METLPGLLQR PDPGALSAAQ LEQLRKFKIQ TRIANEKYLR THKEVEWLIS GFFREIFLKR
     PDNILEFAAD YFTDPRLPNK IHMQLIKDKK AA