RIAD1_MOUSE
ID RIAD1_MOUSE Reviewed; 119 AA.
AC Q3KNY5; Q9D7J0;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-OCT-2013, sequence version 2.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=RIIa domain-containing protein 1;
GN Name=Riiad1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Tongue;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP TISSUE SPECIFICITY.
RX PubMed=17971504; DOI=10.1152/physiolgenomics.00128.2007;
RA McClintock T.S., Glasser C.E., Bose S.C., Bergman D.A.;
RT "Tissue expression patterns identify mouse cilia genes.";
RL Physiol. Genomics 32:198-206(2008).
CC -!- TISSUE SPECIFICITY: Abundant in tissues rich in highly ciliated cells,
CC such as testis, trachea and olfactory epithelium.
CC {ECO:0000269|PubMed:17971504}.
CC -!- CAUTION: It is uncertain whether Met-1 or Met-28 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI07022.1; Type=Miscellaneous discrepancy; Note=Probable cloning artifact.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK009192; BAB26132.1; -; mRNA.
DR EMBL; BC107021; AAI07022.1; ALT_SEQ; mRNA.
DR CCDS; CCDS38535.1; -.
DR RefSeq; NP_079782.1; NM_025506.2.
DR RefSeq; XP_011238492.1; XM_011240190.2.
DR AlphaFoldDB; Q3KNY5; -.
DR BioGRID; 211405; 1.
DR STRING; 10090.ENSMUSP00000029785; -.
DR iPTMnet; Q3KNY5; -.
DR PhosphoSitePlus; Q3KNY5; -.
DR MaxQB; Q3KNY5; -.
DR PaxDb; Q3KNY5; -.
DR PRIDE; Q3KNY5; -.
DR ProteomicsDB; 255268; -.
DR Antibodypedia; 50162; 17 antibodies from 9 providers.
DR DNASU; 66353; -.
DR Ensembl; ENSMUST00000029785; ENSMUSP00000029785; ENSMUSG00000028139.
DR GeneID; 66353; -.
DR KEGG; mmu:66353; -.
DR UCSC; uc008qgk.1; mouse.
DR CTD; 284485; -.
DR MGI; MGI:1913603; Riiad1.
DR VEuPathDB; HostDB:ENSMUSG00000028139; -.
DR eggNOG; ENOG502S8ZF; Eukaryota.
DR GeneTree; ENSGT00390000003062; -.
DR HOGENOM; CLU_144881_1_0_1; -.
DR InParanoid; Q3KNY5; -.
DR OMA; EEAWISF; -.
DR OrthoDB; 1599414at2759; -.
DR PhylomeDB; Q3KNY5; -.
DR TreeFam; TF328360; -.
DR BioGRID-ORCS; 66353; 4 hits in 72 CRISPR screens.
DR ChiTaRS; Riiad1; mouse.
DR PRO; PR:Q3KNY5; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q3KNY5; protein.
DR Bgee; ENSMUSG00000028139; Expressed in spermatid and 85 other tissues.
DR Genevisible; Q3KNY5; MM.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..119
FT /note="RIIa domain-containing protein 1"
FT /id="PRO_0000342468"
FT DOMAIN 70..104
FT /note="RIIa"
SQ SEQUENCE 119 AA; 13797 MW; FB20FAD40273213C CRC64;
MECSASAPEG REEAWISFGK HNNRVCLMET RGHGIVGPDP GTLNPEQLEQ LRDFKIQTRI
ANEKYLRTHK EVSLLISGFF REMFLKRPDN ILEFAAHYFT DPRLPSRIHM QLIKEKKGT
