ID   RIBC2_MOUSE             Reviewed;         377 AA.
AC   Q9D4Q1; G3X8W0;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2019, sequence version 3.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=RIB43A-like with coiled-coils protein 2 {ECO:0000305};
GN   Name=Ribc2 {ECO:0000312|MGI:MGI:1914997};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme, which is required for
CC       motile cilia beating. {ECO:0000250|UniProtKB:Q32LJ7}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:Q32LJ7}.
CC   -!- SIMILARITY: Belongs to the RIB43A family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI12374.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAB30190.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AK016311; BAB30190.2; ALT_INIT; mRNA.
DR   EMBL; AL772308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH466550; EDL04439.1; -; Genomic_DNA.
DR   EMBL; BC112373; AAI12374.1; ALT_INIT; mRNA.
DR   CCDS; CCDS49689.1; -.
DR   RefSeq; NP_080633.2; NM_026357.2.
DR   AlphaFoldDB; Q9D4Q1; -.
DR   SMR; Q9D4Q1; -.
DR   BioGRID; 212415; 4.
DR   STRING; 10090.ENSMUSP00000023067; -.
DR   PhosphoSitePlus; Q9D4Q1; -.
DR   PaxDb; Q9D4Q1; -.
DR   PRIDE; Q9D4Q1; -.
DR   ProteomicsDB; 253283; -.
DR   ProteomicsDB; 329132; -.
DR   Antibodypedia; 303; 98 antibodies from 15 providers.
DR   Ensembl; ENSMUST00000023067; ENSMUSP00000023067; ENSMUSG00000022431.
DR   GeneID; 67747; -.
DR   KEGG; mmu:67747; -.
DR   UCSC; uc007xcz.2; mouse.
DR   CTD; 26150; -.
DR   MGI; MGI:1914997; Ribc2.
DR   VEuPathDB; HostDB:ENSMUSG00000022431; -.
DR   eggNOG; ENOG502QWST; Eukaryota.
DR   GeneTree; ENSGT00390000010825; -.
DR   HOGENOM; CLU_061822_0_1_1; -.
DR   InParanoid; Q9D4Q1; -.
DR   OMA; NYYRCRY; -.
DR   OrthoDB; 1276305at2759; -.
DR   PhylomeDB; Q9D4Q1; -.
DR   TreeFam; TF324120; -.
DR   BioGRID-ORCS; 67747; 2 hits in 74 CRISPR screens.
DR   PRO; PR:Q9D4Q1; -.
DR   Proteomes; UP000000589; Chromosome 15.
DR   RNAct; Q9D4Q1; protein.
DR   Bgee; ENSMUSG00000022431; Expressed in gastrula and 60 other tissues.
DR   ExpressionAtlas; Q9D4Q1; baseline and differential.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   InterPro; IPR008805; RIB43A.
DR   PANTHER; PTHR14517; PTHR14517; 1.
DR   Pfam; PF05914; RIB43A; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..377
FT                   /note="RIB43A-like with coiled-coils protein 2"
FT                   /id="PRO_0000254099"
FT   REGION          354..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          217..246
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  45244 MW;  471DEA326FDF0348 CRC64;
     MEVAMSKDLQ QEANLAKKRY IDLCRQGRIF DARNRIIGGD TQAWDFQVRD QKIKEITDKA
     RHEAFAAEMK HNDKVMCMAH DREQRHRKQL CRAINDFQQN FQKPETRREF DLSDPLALQK
     ELPARISDND MRNTISGMQK FMGEDLNFQE RRRFQKEQSR EWFLQQHGER EKARADHLLA
     EHLHTQTRLK FDETARELMK LEGSTRKEVC AAVKAFNKNQ VVELTERKRQ EKQQEQEDNM
     TEITNLLHGD LLSENPRPVA SSFGSHRVVL DRWKGMNREQ LEEIWFTQKR QIQEKLRLQE
     EERQHSMDWD LRRIRKAHAS LLHERQQQRL LREQRRALDC SNLNLARQQY LQKKQMNTAS
     SSQPTEDYFS QFNTRSR