ID   RIBC2_RAT               Reviewed;         377 AA.
AC   Q6AXN9; R9PXY2;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2019, sequence version 2.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=RIB43A-like with coiled-coils protein 2 {ECO:0000305};
GN   Name=Ribc2 {ECO:0000312|RGD:1309033};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RX   PubMed=15057822; DOI=10.1038/nature02426;
RA   Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
RA   Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
RA   Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
RA   Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
RA   Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
RA   Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
RA   Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
RA   Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
RA   Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
RA   Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
RA   Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
RA   Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
RA   Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
RA   Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
RA   Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
RA   Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
RA   Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
RA   Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
RA   Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
RA   Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
RA   Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
RA   Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
RA   Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
RA   Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
RA   Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
RA   Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
RA   Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
RA   Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
RA   Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
RA   Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
RA   Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
RA   Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
RA   Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
RA   Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
RA   Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
RA   Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
RA   Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
RA   Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
RA   Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
RA   Mockrin S., Collins F.S.;
RT   "Genome sequence of the Brown Norway rat yields insights into mammalian
RT   evolution.";
RL   Nature 428:493-521(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Brown Norway;
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme, which is required for
CC       motile cilia beating. {ECO:0000250|UniProtKB:Q32LJ7}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:Q32LJ7}.
CC   -!- SIMILARITY: Belongs to the RIB43A family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH79434.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AABR07058587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH473950; EDM15587.1; -; Genomic_DNA.
DR   EMBL; BC079434; AAH79434.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001013971.2; NM_001013949.1.
DR   AlphaFoldDB; Q6AXN9; -.
DR   SMR; Q6AXN9; -.
DR   IntAct; Q6AXN9; 1.
DR   STRING; 10116.ENSRNOP00000041528; -.
DR   CarbonylDB; Q6AXN9; -.
DR   PaxDb; Q6AXN9; -.
DR   Ensembl; ENSRNOT00000042412; ENSRNOP00000041528; ENSRNOG00000033502.
DR   GeneID; 300122; -.
DR   KEGG; rno:300122; -.
DR   CTD; 26150; -.
DR   RGD; 1309033; Ribc2.
DR   eggNOG; ENOG502QWST; Eukaryota.
DR   GeneTree; ENSGT00390000010825; -.
DR   HOGENOM; CLU_061822_0_1_1; -.
DR   InParanoid; Q6AXN9; -.
DR   OMA; NYYRCRY; -.
DR   OrthoDB; 1276305at2759; -.
DR   PhylomeDB; Q6AXN9; -.
DR   TreeFam; TF324120; -.
DR   PRO; PR:Q6AXN9; -.
DR   Proteomes; UP000002494; Chromosome 7.
DR   Proteomes; UP000234681; Chromosome 7.
DR   Bgee; ENSRNOG00000033502; Expressed in testis and 2 other tissues.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   InterPro; IPR008805; RIB43A.
DR   PANTHER; PTHR14517; PTHR14517; 1.
DR   Pfam; PF05914; RIB43A; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Coiled coil; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..377
FT                   /note="RIB43A-like with coiled-coils protein 2"
FT                   /id="PRO_0000254100"
FT   REGION          355..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          188..238
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   377 AA;  45134 MW;  D0A532FEB4B28C17 CRC64;
     MEVAIPKDLQ QEASLAKKRY MDLCRQGQIF DARNRIIGGD TQAWDVQVRN QKIKEVTEKA
     RDETFAAEMR HNDKVMCIMH DRELRHRKQL CRAINDFQQR FQKPETRREF DLSDPLALKK
     ELPARVSDND MRNTISGMQK FMGEDLNFQE RKRIQKEQNR EWSLQQHGEW ERAQAEHKLA
     EHLHTQTELK FDEAARDLQR LEITTRKAVC AAVKEFNKKQ VVELAERKRQ VKQQEQEDNM
     SEITNLLHGD LLSENPQQAA SNFGPRHVML DRWKGMNREQ LEEIWSTWKQ QIHEKLRLQE
     EERQHNMDWD LRRTRKAHAS LLQERQQQRL LREQRRALDC SNLSLAKQQY LQKRQLDAAP
     SSQPTEDYFS QFNTRSR