RIC6_ARATH
ID RIC6_ARATH Reviewed; 212 AA.
AC Q1PF35; A0MEN4; Q9SIM6;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=CRIB domain-containing protein RIC6;
DE AltName: Full=ROP-interactive CRIB motif-containing protein 6;
DE AltName: Full=Target of ROP protein RIC6;
GN Name=RIC6; OrderedLocusNames=At2g20430; ORFNames=T13C7.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP FUNCTION, INTERACTION WITH ARAC11/ROP1, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11752391; DOI=10.2307/3871538;
RA Wu G., Gu Y., Li S., Yang Z.;
RT "A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-
RT containing proteins that act as Rop GTPase targets.";
RL Plant Cell 13:2841-2856(2001).
CC -!- FUNCTION: Functions as downstream effector of Rho-related GTP binding
CC proteins of the 'Rho of Plants' (ROPs) family. Participates in the
CC propagation of ROP GTPase signals in specific cellular responses. Is
CC involved in pollen tube growth regulation through its interaction with
CC ARAC11/ROP1. {ECO:0000269|PubMed:11752391}.
CC -!- SUBUNIT: Interacts with ARAC11/ROP1. {ECO:0000269|PubMed:11752391}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:11752391};
CC Peripheral membrane protein {ECO:0000305|PubMed:11752391}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers and pollen.
CC {ECO:0000269|PubMed:11752391}.
CC -!- MISCELLANEOUS: Over-expression of RIC6 in tobacco germinating pollen
CC reduces pollen tube elongation. {ECO:0000305|PubMed:11752391}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD25644.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAM15282.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=ABK28502.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC006569; AAM15282.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC007109; AAD25644.2; ALT_INIT; Genomic_DNA.
DR EMBL; CP002685; AEC07006.1; -; Genomic_DNA.
DR EMBL; DQ446531; ABE65834.1; -; mRNA.
DR EMBL; DQ653006; ABK28502.1; ALT_SEQ; mRNA.
DR PIR; B84589; B84589.
DR RefSeq; NP_179633.2; NM_127602.4.
DR AlphaFoldDB; Q1PF35; -.
DR BioGRID; 1915; 1.
DR STRING; 3702.AT2G20430.1; -.
DR PaxDb; Q1PF35; -.
DR PRIDE; Q1PF35; -.
DR ProteomicsDB; 236984; -.
DR EnsemblPlants; AT2G20430.1; AT2G20430.1; AT2G20430.
DR GeneID; 816562; -.
DR Gramene; AT2G20430.1; AT2G20430.1; AT2G20430.
DR KEGG; ath:AT2G20430; -.
DR Araport; AT2G20430; -.
DR TAIR; locus:2054820; AT2G20430.
DR eggNOG; ENOG502S2ZY; Eukaryota.
DR HOGENOM; CLU_086489_2_0_1; -.
DR InParanoid; Q1PF35; -.
DR OMA; SIKCMSE; -.
DR OrthoDB; 1458444at2759; -.
DR PhylomeDB; Q1PF35; -.
DR PRO; PR:Q1PF35; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q1PF35; baseline and differential.
DR Genevisible; Q1PF35; AT.
DR GO; GO:0016324; C:apical plasma membrane; IDA:TAIR.
DR GO; GO:0009860; P:pollen tube growth; IMP:TAIR.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR Gene3D; 3.90.810.10; -; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR044510; RIC1-like.
DR PANTHER; PTHR46325; PTHR46325; 1.
DR Pfam; PF00786; PBD; 1.
DR SMART; SM00285; PBD; 1.
DR PROSITE; PS50108; CRIB; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Growth regulation; Membrane; Reference proteome.
FT CHAIN 1..212
FT /note="CRIB domain-containing protein RIC6"
FT /id="PRO_0000422729"
FT DOMAIN 34..47
FT /note="CRIB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00057"
FT REGION 51..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 212 AA; 23346 MW; 3DF239BC9E95B1C8 CRC64;
MQLTMSSSKM KSLLKGLRYI SQVFESEKEE EIQIGNPTDV KHVAHIGWDG PSANATAPSW
MTEFNSGGGF ESAEGVGEDD SSIKCMSEYG GRSRDLPNLP KSTRKAASEK GSPTKDKSSD
KTKRRSSNKG TSSSSRRPKE ATEEQDELSS WPSGLPEIPK KSRRKKKSTK ETAVNGGSSR
STRRSDVDNM SEYMSETGSV RSMPQFDNRD DF
