RIC8_ARATH
ID RIC8_ARATH Reviewed; 177 AA.
AC Q9ZWB8;
DT 26-JUN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=CRIB domain-containing protein RIC8;
DE AltName: Full=ROP-interactive CRIB motif-containing protein 8;
DE AltName: Full=Target of ROP protein RIC8;
GN Name=RIC8; OrderedLocusNames=At1g03982; ORFNames=F21M11.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11752391; DOI=10.2307/3871538;
RA Wu G., Gu Y., Li S., Yang Z.;
RT "A genome-wide analysis of Arabidopsis Rop-interactive CRIB motif-
RT containing proteins that act as Rop GTPase targets.";
RL Plant Cell 13:2841-2856(2001).
CC -!- FUNCTION: Functions as downstream effector of Rho-related GTP binding
CC proteins of the 'Rho of Plants' (ROPs) family. Participates in the
CC propagation of ROP GTPase signals in specific cellular responses (By
CC similarity). {ECO:0000250}.
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DR EMBL; AC003027; AAD10672.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27642.1; -; Genomic_DNA.
DR EMBL; DQ487432; ABF59176.1; -; mRNA.
DR PIR; H86170; H86170.
DR RefSeq; NP_001030953.1; NM_001035876.2.
DR AlphaFoldDB; Q9ZWB8; -.
DR STRING; 3702.AT1G03982.1; -.
DR PaxDb; Q9ZWB8; -.
DR PRIDE; Q9ZWB8; -.
DR EnsemblPlants; AT1G03982.1; AT1G03982.1; AT1G03982.
DR GeneID; 3766656; -.
DR Gramene; AT1G03982.1; AT1G03982.1; AT1G03982.
DR KEGG; ath:AT1G03982; -.
DR Araport; AT1G03982; -.
DR TAIR; locus:1009023072; AT1G03982.
DR eggNOG; ENOG502S2ZY; Eukaryota.
DR HOGENOM; CLU_086489_2_0_1; -.
DR InParanoid; Q9ZWB8; -.
DR OMA; WMKDFNG; -.
DR OrthoDB; 1384435at2759; -.
DR PhylomeDB; Q9ZWB8; -.
DR PRO; PR:Q9ZWB8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9ZWB8; differential.
DR Gene3D; 3.90.810.10; -; 1.
DR InterPro; IPR000095; CRIB_dom.
DR InterPro; IPR036936; CRIB_dom_sf.
DR InterPro; IPR044510; RIC1-like.
DR PANTHER; PTHR46325; PTHR46325; 1.
DR Pfam; PF00786; PBD; 1.
DR SMART; SM00285; PBD; 1.
DR PROSITE; PS50108; CRIB; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..177
FT /note="CRIB domain-containing protein RIC8"
FT /id="PRO_0000422731"
FT DOMAIN 17..30
FT /note="CRIB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00057"
FT REGION 72..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..157
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 177 AA; 19411 MW; 40094A614A167735 CRC64;
MINLHNAENE KEAEMQIGTP TDVKHVAHIG WDGGSVNHNP PSWMKDFKVL GGYSPALIGN
IKEDASCIFE DSTRSRDIPR LPKSSRERSS TLGGSPTKER SRRRGSSQYN GNPKVSRRSS
KESSAIPQDG GFNKKSRRKK SKDCVDGGSR RSSRRVRGSQ VESISDSSST SDAGYLT