ID   RIG_HUMAN               Reviewed;         110 AA.
AC   Q13278;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Putative protein RIG;
DE   AltName: Full=Protein regulated in glioma;
GN   Name=RIG;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
RC   TISSUE=Brain;
RX   PubMed=9070656; DOI=10.1038/sj.onc.1200925;
RA   Ligon A.H., Pershouse M.A., Jasser S.A., Yung W.K.A., Steck P.A.;
RT   "Identification of a novel gene product, RIG, that is down-regulated in
RT   human glioblastoma.";
RL   Oncogene 14:1075-1081(1997).
CC   -!- FUNCTION: May serve as a molecular marker for or play a role in the
CC       malignant progression of glioblastomas. {ECO:0000269|PubMed:9070656}.
CC   -!- TISSUE SPECIFICITY: Expressed predominantly in brain and weakly in
CC       heart and lung. Expression is reduced or undetectable in cultured
CC       glioma cells, primary glioblastoma cells and malignant glioblastoma
CC       tumors. {ECO:0000269|PubMed:9070656}.
CC   -!- CAUTION: Product of a dubious CDS prediction. {ECO:0000305}.
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DR   EMBL; U32331; AAC35996.1; -; mRNA.
DR   PIR; G01973; G01973.
DR   AlphaFoldDB; Q13278; -.
DR   iPTMnet; Q13278; -.
DR   PhosphoSitePlus; Q13278; -.
DR   BioMuta; RIG; -.
DR   PRIDE; Q13278; -.
DR   neXtProt; NX_Q13278; -.
DR   PathwayCommons; Q13278; -.
DR   Pharos; Q13278; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q13278; protein.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..110
FT                   /note="Putative protein RIG"
FT                   /id="PRO_0000347326"
SQ   SEQUENCE   110 AA;  11984 MW;  0E172BDCCA46F7BA CRC64;
     MPFFSSCLCP SHYSGPSLPS STSSSLPTGP ENQLGFVLLQ AMVHHANSSC VRNAFWLQIT
     EKLTPALSII ISVVYLRCPE MVENRIGFLL NVKDSKTLSV VGPHPKPCIL