ID   RIMP_MYCTU              Reviewed;         183 AA.
AC   P9WH17; L0TDI5; O05817; P67214;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Ribosome maturation factor RimP {ECO:0000255|HAMAP-Rule:MF_01077};
GN   Name=rimP {ECO:0000255|HAMAP-Rule:MF_01077}; OrderedLocusNames=Rv2842c;
GN   ORFNames=MTCY24A1.15;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION AS A DRUG TARGET [LARGE SCALE ANALYSIS].
RX   PubMed=19099550; DOI=10.1186/1752-0509-2-109;
RA   Raman K., Yeturu K., Chandra N.;
RT   "targetTB: a target identification pipeline for Mycobacterium tuberculosis
RT   through an interactome, reactome and genome-scale structural analysis.";
RL   BMC Syst. Biol. 2:109-109(2008).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- FUNCTION: Required for maturation of 30S ribosomal subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_01077}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01077}.
CC   -!- MISCELLANEOUS: Was identified as a high-confidence drug target.
CC   -!- SIMILARITY: Belongs to the RimP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01077}.
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DR   EMBL; AL123456; CCP45643.1; -; Genomic_DNA.
DR   PIR; E70588; E70588.
DR   RefSeq; NP_217358.1; NC_000962.3.
DR   RefSeq; WP_003899507.1; NZ_NVQJ01000006.1.
DR   AlphaFoldDB; P9WH17; -.
DR   SMR; P9WH17; -.
DR   STRING; 83332.Rv2842c; -.
DR   PaxDb; P9WH17; -.
DR   DNASU; 888159; -.
DR   GeneID; 45426829; -.
DR   GeneID; 888159; -.
DR   KEGG; mtu:Rv2842c; -.
DR   TubercuList; Rv2842c; -.
DR   eggNOG; COG0779; Bacteria.
DR   OMA; TEHRHYV; -.
DR   PhylomeDB; P9WH17; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd01734; YlxS_C; 1.
DR   Gene3D; 3.30.300.70; -; 1.
DR   HAMAP; MF_01077; RimP; 1.
DR   InterPro; IPR003728; Ribosome_maturation_RimP.
DR   InterPro; IPR028998; RimP_C.
DR   InterPro; IPR036847; RimP_C_sf.
DR   InterPro; IPR028989; RimP_N.
DR   InterPro; IPR035956; RimP_N_sf.
DR   PANTHER; PTHR33867; PTHR33867; 1.
DR   Pfam; PF02576; DUF150; 1.
DR   Pfam; PF17384; DUF150_C; 1.
DR   SUPFAM; SSF74942; SSF74942; 1.
DR   SUPFAM; SSF75420; SSF75420; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..183
FT                   /note="Ribosome maturation factor RimP"
FT                   /id="PRO_0000181892"
SQ   SEQUENCE   183 AA;  19565 MW;  52BF821CECF7BB3B CRC64;
     MTTGLPSQRQ VIELLGADFA CAGYEIEDVV IDARARPPRI AVIADGDAPL DLDTIAALSR
     RASALLDGLD GANKIRGRYL LEVSSPGVER PLTSEKHFRR ARGRKVELVL SDGSRLTGRV
     GEMRAGTVAL VIREDRGWAV REIPLAEIVK AVVQVEFSPP APAELELAQS SEMGLARGTE
     AGA