ID   RIPL1_XENLA             Reviewed;         394 AA.
AC   Q0IHE5;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=RILP-like protein 1;
DE   AltName: Full=Rab-interacting lysosomal-like protein 1;
GN   Name=rilpl1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Fat body;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the regulation of cell shape and polarity.
CC       Plays a role in cellular protein transport, including protein transport
CC       away from primary cilia. Neuroprotective protein (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
CC       Cell projection, cilium {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RILPL family. {ECO:0000305}.
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DR   EMBL; BC123187; AAI23188.1; -; mRNA.
DR   RefSeq; NP_001090335.1; NM_001096866.1.
DR   AlphaFoldDB; Q0IHE5; -.
DR   SMR; Q0IHE5; -.
DR   DNASU; 779245; -.
DR   GeneID; 779245; -.
DR   KEGG; xla:779245; -.
DR   CTD; 779245; -.
DR   Xenbase; XB-GENE-17338188; rilpl1.L.
DR   OMA; NHELHGA; -.
DR   OrthoDB; 890179at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 779245; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR   GO; GO:0005829; C:cytosol; ISS:UniProtKB.
DR   GO; GO:0016020; C:membrane; IEA:GOC.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:1903445; P:protein transport from ciliary membrane to plasma membrane; ISS:UniProtKB.
DR   GO; GO:1901214; P:regulation of neuron death; ISS:UniProtKB.
DR   InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   InterPro; IPR021563; RILP_dimer.
DR   Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR   Pfam; PF11461; RILP; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..394
FT                   /note="RILP-like protein 1"
FT                   /id="PRO_0000299313"
FT   DOMAIN          2..89
FT                   /note="RH1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01112"
FT   DOMAIN          282..347
FT                   /note="RH2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01113"
FT   COILED          68..327
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   394 AA;  46590 MW;  108ED85FFEF4471E CRC64;
     MEGISALEKN VAELTVMDVY DIASAVGQEF ERVIDQYGCE VIGRLMPKVV RVLEILEVLV
     SRNHINPEME ELRLELDRLR LERMDRIEKE KKHLKELELV EDVWRGEAQD LLNQISQLQE
     ENKQLLTNLS HKDVNLTEEE FQKHEGMSER ERQVMKKLKE VVDKQRDEIR ARDRELVLKN
     EDVEALQQQQ SRLIKINHDL RHRVTVVEAQ GKALIEQKVE LEAYLQTKEQ EAASMRIEIG
     KLRDKLKGEH HTNGEEIKTE TLNEECIFET EKFSLDLKDS NRPRFTLQEL RDVLHERNEL
     KAKVFMLQEE LAYYKSEEAE EENKLPQSLP VINSKAPIPQ ESGIKRLFSF FSRDKKRMPM
     MQKNVHFQES FGEWTNYNRD DVYTEQGQEA LQHM