ID   RIPL1_XENTR             Reviewed;         394 AA.
AC   A0PJP4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=RILP-like protein 1;
DE   AltName: Full=Rab-interacting lysosomal-like protein 1;
GN   Name=rilpl1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the regulation of cell shape and polarity.
CC       Plays a role in cellular protein transport, including protein transport
CC       away from primary cilia. Neuroprotective protein (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
CC       Cell projection, cilium {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RILPL family. {ECO:0000305}.
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DR   EMBL; BC127552; AAI27553.1; -; mRNA.
DR   EMBL; BC135712; AAI35713.1; -; mRNA.
DR   RefSeq; NP_001096320.1; NM_001102850.1.
DR   AlphaFoldDB; A0PJP4; -.
DR   SMR; A0PJP4; -.
DR   STRING; 8364.ENSXETP00000060379; -.
DR   PaxDb; A0PJP4; -.
DR   DNASU; 100124903; -.
DR   GeneID; 100124903; -.
DR   KEGG; xtr:100124903; -.
DR   CTD; 353116; -.
DR   Xenbase; XB-GENE-952710; rilpl1.
DR   eggNOG; ENOG502QR9G; Eukaryota.
DR   HOGENOM; CLU_044133_3_0_1; -.
DR   InParanoid; A0PJP4; -.
DR   OrthoDB; 890179at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000032256; Expressed in skeletal muscle tissue and 15 other tissues.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR   GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; ISS:UniProtKB.
DR   GO; GO:0016020; C:membrane; IEA:GOC.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:1903445; P:protein transport from ciliary membrane to plasma membrane; ISS:UniProtKB.
DR   GO; GO:1901214; P:regulation of neuron death; ISS:UniProtKB.
DR   InterPro; IPR019143; JNK/Rab-associated_protein-1_N.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   InterPro; IPR021563; RILP_dimer.
DR   Pfam; PF09744; Jnk-SapK_ap_N; 1.
DR   Pfam; PF11461; RILP; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..394
FT                   /note="RILP-like protein 1"
FT                   /id="PRO_0000299314"
FT   DOMAIN          2..89
FT                   /note="RH1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01112"
FT   DOMAIN          282..347
FT                   /note="RH2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01113"
FT   REGION          318..337
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          68..312
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   394 AA;  46461 MW;  0B93F2B42339840D CRC64;
     MEGISALEKN VAELTVMDVY DIASAVGQEF ERVIDQYGCE VIGRLMPKVV RVLEILEVLV
     SRNHINPEME ELRLELDRLR LERMDRIEKE KKHQKELELV EDVWRGEAQD LLNQIAQLQE
     ENKQLVSNLS QKDINLTEEE FQKHEGMSER ERQVMKKLKE VVDKQRDEIR AKDRELVLKN
     EDVEALQQQQ SRLMKINHDL RHRVTVVEAQ GKALIEQKVE LEAYLQTKEQ EAASMRLEIG
     KLRDKLKGEQ HTNGEEIKTE TLNEESILET EKLSLDLKDS NRPRFTLQEL RDVLHERNEL
     KAKVFMLQEE LAYYKSEEAD EEHKLPQSSP VIDSKAPIPQ ESGIKRLFSF FSRDKKRMPM
     MQKNVHFQES FGQWTEYNRD DVYTEQGQEA LQHM