ID   RIPL2_XENLA             Reviewed;         201 AA.
AC   Q6IP02;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 2.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=RILP-like protein 2;
DE   AltName: Full=Rab-interacting lysosomal-like protein 2;
GN   Name=rilpl2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in cell shape and neuronal morphogenesis, positively
CC       regulating the establishment and maintenance of dendritic spines. Plays
CC       a role in cellular protein transport (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
CC       Cell projection, cilium {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RILPL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH72117.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC072117; AAH72117.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001085096.2; NM_001091627.1.
DR   AlphaFoldDB; Q6IP02; -.
DR   SMR; Q6IP02; -.
DR   DNASU; 432167; -.
DR   GeneID; 432167; -.
DR   KEGG; xla:432167; -.
DR   CTD; 432167; -.
DR   Xenbase; XB-GENE-5715356; rilpl2.L.
DR   OrthoDB; 890179at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 432167; Expressed in testis and 19 other tissues.
DR   GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR   GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:GOC.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR   GO; GO:1903445; P:protein transport from ciliary membrane to plasma membrane; ISS:UniProtKB.
DR   InterPro; IPR034743; RH1.
DR   InterPro; IPR034744; RH2.
DR   InterPro; IPR021563; RILP_dimer.
DR   Pfam; PF11461; RILP; 1.
DR   PROSITE; PS51776; RH1; 1.
DR   PROSITE; PS51777; RH2; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Protein transport; Reference proteome; Transport.
FT   CHAIN           1..201
FT                   /note="RILP-like protein 2"
FT                   /id="PRO_0000317009"
FT   DOMAIN          14..108
FT                   /note="RH1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01112"
FT   DOMAIN          121..197
FT                   /note="RH2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01113"
FT   REGION          175..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          67..155
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   201 AA;  22752 MW;  CFC9B5C638768000 CRC64;
     METEQDEMGQ EEMSPEMALD KDPFQLTVED VYDISHVVGQ DLLKINREAR GVSSLVSDLQ
     FKIVRVLEML EALVNQSSLS AEELKMERDN LKAEVDRLLR DGPQMGVGPD KMVIDLTDPN
     RPRFTLQELR DVLQERNKLK VQLLVAQDEL QCYKSGIIPS PDDQIVTLEN ESIITSSPRS
     NASKEKSTVK SLFSFKQGKN T