RIPL2_XENTR
ID RIPL2_XENTR Reviewed; 201 AA.
AC Q0P4J3;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=RILP-like protein 2;
DE AltName: Full=Rab-interacting lysosomal-like protein 2;
GN Name=rilpl2;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6; TISSUE=Oviduct;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell shape and neuronal morphogenesis, positively
CC regulating the establishment and maintenance of dendritic spines. Plays
CC a role in cellular protein transport (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000250}. Cytoplasm,
CC cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
CC Cell projection, cilium {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RILPL family. {ECO:0000305}.
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DR EMBL; BC122050; AAI22051.1; -; mRNA.
DR RefSeq; NP_001072546.2; NM_001079078.2.
DR RefSeq; XP_012820894.1; XM_012965440.2.
DR AlphaFoldDB; Q0P4J3; -.
DR SMR; Q0P4J3; -.
DR PaxDb; Q0P4J3; -.
DR DNASU; 780001; -.
DR GeneID; 780001; -.
DR KEGG; xtr:780001; -.
DR CTD; 196383; -.
DR Xenbase; XB-GENE-5715323; rilpl2.
DR eggNOG; ENOG502S08B; Eukaryota.
DR InParanoid; Q0P4J3; -.
DR OrthoDB; 890179at2759; -.
DR Proteomes; UP000008143; Chromosome 1.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0036064; C:ciliary basal body; IBA:GO_Central.
DR GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:GOC.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
DR GO; GO:1903445; P:protein transport from ciliary membrane to plasma membrane; ISS:UniProtKB.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR021563; RILP_dimer.
DR Pfam; PF11461; RILP; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton;
KW Protein transport; Reference proteome; Transport.
FT CHAIN 1..201
FT /note="RILP-like protein 2"
FT /id="PRO_0000317010"
FT DOMAIN 14..108
FT /note="RH1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01112"
FT DOMAIN 121..197
FT /note="RH2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01113"
FT REGION 177..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 67..155
FT /evidence="ECO:0000255"
SQ SEQUENCE 201 AA; 22775 MW; 3185CBBEE09867A2 CRC64;
METEQDEVAQ DELGPEIALD KDPFQLTVED VYDISHIVGQ DLLKISREAR GVSSLVSDLQ
FKIVRVLEML EALVNQSSLS AEELKMERDN LKAEVERLLK DGPQMGVGPD KMVIDLTDPN
RPRFTLQELR DVLQERNKLK VKLLVAQDEL QCYKSGIIPS PDDQIVTLEN ESMITCSPRE
NESKEKSTVK SLFSFKQGKQ T