RITF1_ARATH
ID RITF1_ARATH Reviewed; 256 AA.
AC Q1G3Q4; A0A178W1S1;
DT 10-FEB-2021, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Protein RGF1 INDUCIBLE TRANSCRIPTION FACTOR 1 {ECO:0000303|PubMed:31801996};
GN Name=RITF1 {ECO:0000303|PubMed:31801996};
GN OrderedLocusNames=At2g12646 {ECO:0000312|Araport:AT2G12646};
GN ORFNames=T4E5 {ECO:0000312|EMBL:AC007295};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY RGF1 PEPTIDE, AND TISSUE
RP SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=31801996; DOI=10.1038/s41586-019-1819-6;
RA Yamada M., Han X., Benfey P.N.;
RT "RGF1 controls root meristem size through ROS signalling.";
RL Nature 577:85-88(2020).
CC -!- FUNCTION: Probable transcription factor that plays a central role in
CC mediating RGF1 hormone peptide signaling leading to the production of
CC reactive oxygen species (ROS) in roots to modulate meristem size and
CC root growth, probably via oxidative post-translational modification of
CC the transcription factor PLETHORA (e.g. PLT1 and PLT2).
CC {ECO:0000269|PubMed:31801996}.
CC -!- INTERACTION:
CC Q1G3Q4; Q1G3I2: MIP1A; NbExp=3; IntAct=EBI-15193003, EBI-15191905;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed predominantly in root meristematic zones.
CC {ECO:0000269|PubMed:31801996}.
CC -!- INDUCTION: Induced by RGF1 peptides. {ECO:0000269|PubMed:31801996}.
CC -!- DISRUPTION PHENOTYPE: Small root meristem and low root growth rate.
CC {ECO:0000269|PubMed:31801996}.
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DR EMBL; AC007295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC06206.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62409.1; -; Genomic_DNA.
DR EMBL; DQ487530; ABF59218.1; -; mRNA.
DR RefSeq; NP_001031352.1; NM_001036275.3.
DR RefSeq; NP_001324567.1; NM_001335382.1.
DR AlphaFoldDB; Q1G3Q4; -.
DR IntAct; Q1G3Q4; 14.
DR STRING; 3702.AT2G12646.1; -.
DR PaxDb; Q1G3Q4; -.
DR PRIDE; Q1G3Q4; -.
DR ProteomicsDB; 189213; -.
DR EnsemblPlants; AT2G12646.1; AT2G12646.1; AT2G12646.
DR EnsemblPlants; AT2G12646.2; AT2G12646.2; AT2G12646.
DR GeneID; 3768403; -.
DR Gramene; AT2G12646.1; AT2G12646.1; AT2G12646.
DR Gramene; AT2G12646.2; AT2G12646.2; AT2G12646.
DR KEGG; ath:AT2G12646; -.
DR Araport; AT2G12646; -.
DR TAIR; locus:1009023224; AT2G12646.
DR eggNOG; ENOG502R0ZN; Eukaryota.
DR HOGENOM; CLU_070437_3_0_1; -.
DR InParanoid; Q1G3Q4; -.
DR OrthoDB; 1056401at2759; -.
DR PhylomeDB; Q1G3Q4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q1G3Q4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0010078; P:maintenance of root meristem identity; IMP:UniProtKB.
DR GO; GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:UniProtKB.
DR GO; GO:2000280; P:regulation of root development; IMP:UniProtKB.
DR GO; GO:0043434; P:response to peptide hormone; IEP:UniProtKB.
DR InterPro; IPR006734; PLATZ.
DR Pfam; PF04640; PLATZ; 1.
PE 1: Evidence at protein level;
KW Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..256
FT /note="Protein RGF1 INDUCIBLE TRANSCRIPTION FACTOR 1"
FT /id="PRO_0000451978"
FT ZN_FING 21..59
FT /note="B box-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
SQ SEQUENCE 256 AA; 28849 MW; D5901B0342AB6C79 CRC64;
MGIQKPAWLD ALYAEKFFVG CPYHETAKKN ERNVCCLDCC TSLCPHCVPS HRFHRLLQVR
RYVYHDVVRL EDLQKLIDCS NVQAYTINSA KVVFIKKRPQ NRQFKGAGNY CTSCDRSLQE
PYIHCSLGCK VDFVMKRYRD ITPFLKPCHT LTLGPDYIIP QDLLTDDEVA AYETPRSTVV
DGDESMSWSS ASSDNNNAGA AAAYAATTTH VVRKKRTGFC LCAKSANSYK EVSEDPDDIS
ACINRRKGVP QRSPLC
