RKD4_PYRCJ
ID RKD4_PYRCJ Reviewed; 795 AA.
AC A3MWN7;
DT 15-MAR-2017, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Arcadin-4 {ECO:0000303|PubMed:21414041};
GN Name=rkd-4 {ECO:0000303|PubMed:21414041};
GN OrderedLocusNames=Pcal_1637 {ECO:0000312|EMBL:ABO09054.1};
OS Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1).
OC Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Pyrobaculum.
OX NCBI_TaxID=410359;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21063 / JCM 11548 / VA1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Cozen A.E.,
RA Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.;
RT "Complete sequence of Pyrobaculum calidifontis JCM 11548.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=21414041; DOI=10.1111/j.1365-2958.2011.07635.x;
RA Ettema T.J., Lindaas A.C., Bernander R.;
RT "An actin-based cytoskeleton in archaea.";
RL Mol. Microbiol. 80:1052-1061(2011).
CC -!- FUNCTION: Part of an actin-like archaeal cytoskeleton.
CC {ECO:0000269|PubMed:21414041}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000305}. Note=Forms
CC cell-spanning helical structures. {ECO:0000269|PubMed:21414041}.
CC -!- MISCELLANEOUS: Belongs to a conserved five-gene operon within
CC Thermoproteales denoted Arcade (actin-related cytoskeleton in Archaea
CC involved in shape determination). {ECO:0000305|PubMed:21414041}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000561; ABO09054.1; -; Genomic_DNA.
DR AlphaFoldDB; A3MWN7; -.
DR STRING; 410359.Pcal_1637; -.
DR EnsemblBacteria; ABO09054; ABO09054; Pcal_1637.
DR KEGG; pcl:Pcal_1637; -.
DR eggNOG; arCOG00368; Archaea.
DR HOGENOM; CLU_004785_0_2_2; -.
DR OMA; PYVDVNI; -.
DR Proteomes; UP000001431; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; -; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR Pfam; PF13476; AAA_23; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 4: Predicted;
KW Coiled coil; Cytoplasm; Cytoskeleton.
FT CHAIN 1..795
FT /note="Arcadin-4"
FT /id="PRO_0000439075"
FT COILED 205..253
FT /evidence="ECO:0000255"
FT COILED 323..412
FT /evidence="ECO:0000255"
FT COILED 450..618
FT /evidence="ECO:0000255"
SQ SEQUENCE 795 AA; 90174 MW; E30E85C10CC8DC65 CRC64;
MWRISRVELE NFRSYRGAHR LELGDVNLLW GRIGAGKTSV FYAIEYALFG QQLEVKERVA
KLADLIHSGS HEARVALELV DGANVLKVER KLGKRGAEKL VVVHNGVELR GGEAERRLEE
LLGVDEDLYE RLVYISHRTL EGFIYGTSQK RAISVDRLFG IDVIDGVVKT VSSAEKALLG
KAEELRKRLA AYEKYRDVIK RYGGYSGLVS RLRALSSEIE ALKEREAMLT RTVEELARAR
AAYLAKLKEH EQILLEYYRA RSELEFLESS AGGEVDVGAL EKVKAALREA AEEFEHMLDP
GILEKLYKAS DLEALSVAMA EVYDALTRVA KDLELELTDV KKAYEEYVAR ARRLEEEVAA
AEARLRRLEK PFLRFQELLK KLRSLEEARA RLSEARRRLS EAEREAAYYT SLKTVALYLA
ETNASVCPIC GSPISREAVE KVVRDIDEKF GGVVKRVEEL REEVKALERE VEEMEILQGD
AAEYIAAKAR LDELKVEREE VVKKVLQAEK SVRQLEKRIE KLREFFAKVD KRVISDAVSR
YGRAVRIREL RKRVKELEER LRQAGIGGEE LEVEVKWREA AAELEKAAAR LAELYKEKSL
LEEAAREVGE EAEGLKKRLD NVLYAYGRLE ELKSRLELAK VSARARLVEV VRSRFNEVFQ
SLYKYGDVVK VDAAVEPSRG YYDFYAISPS GDRYGVSRLS DGQRLSIALS LALALREISQ
VKLGFLIFDE PIPYVDVNVR KAFAQLLTSL AGRYQLLVAT QSREFAEEVR EALPNAKLFT
VVKDGASALI EGLQS