位置:首页 > 蛋白库 > RKM5_VANPO
RKM5_VANPO
ID   RKM5_VANPO              Reviewed;         324 AA.
AC   A7TTV0;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   03-AUG-2022, entry version 44.
DE   RecName: Full=Ribosomal lysine N-methyltransferase 5 {ECO:0000250|UniProtKB:Q12367};
DE            EC=2.1.1.- {ECO:0000250|UniProtKB:Q12367};
GN   Name=RKM5; ORFNames=Kpol_152p1;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent protein-lysine N-
CC       methyltransferase that methylates 60S ribosomal protein L1.
CC       {ECO:0000250|UniProtKB:Q12367}.
CC   -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC       superfamily. RKM5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EDO14306.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS480632; EDO14306.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_001642164.1; XM_001642114.1.
DR   AlphaFoldDB; A7TTV0; -.
DR   STRING; 436907.A7TTV0; -.
DR   EnsemblFungi; EDO14306; EDO14306; Kpol_152p1.
DR   GeneID; 5542277; -.
DR   KEGG; vpo:Kpol_152p1; -.
DR   eggNOG; KOG1018; Eukaryota.
DR   HOGENOM; CLU_051532_0_0_1; -.
DR   InParanoid; A7TTV0; -.
DR   OrthoDB; 1346733at2759; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006479; P:protein methylation; IEA:UniProt.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR019410; Methyltransf_16.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR14614; PTHR14614; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..324
FT                   /note="Ribosomal lysine N-methyltransferase 5"
FT                   /id="PRO_0000411044"
FT   BINDING         90
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H867"
FT   BINDING         140..142
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H867"
FT   BINDING         162
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H867"
FT   BINDING         217
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H867"
FT   BINDING         247
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250|UniProtKB:Q9H867"
SQ   SEQUENCE   324 AA;  36820 MW;  750044E3D0D15863 CRC64;
     MSGLLQLDEE SLYDHIFERY TLLTSNNDSL KQDLGIVDRT VSKITIDIDQ FDFNNKKSNN
     DFYSIEINQP ITSLNSSSVN NNSTTGYVVW STTPFFTRWL IFHSNASIFR NGGSIELIDQ
     DDELKLPPMF SNSVGLLELG SGIAGILPVT LGNFVGSFIA TDQIGILSTL KTNILENLSQ
     LNRKIVTSRS LNLNLDVDES TLLKRSLLSL ECLPLDWELF DIKDTTKLDP ALLSLFKEKE
     TIYVLAMDVI YNEYLIESFL STIQNLKSLA FKFNVNLNCL IGIQLRSEEV TTLFLEKAII
     DYEMKVYYIQ DNILESSRFS IYMI
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024