ID   RL102_PLAVT             Reviewed;         477 AA.
AC   P0CV40;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 1.
DT   25-MAY-2022, entry version 9.
DE   RecName: Full=Secreted RxLR effector protein 102 {ECO:0000303|PubMed:29706971};
DE   Flags: Precursor;
GN   Name=RXLR102 {ECO:0000303|PubMed:29706971};
OS   Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=143451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA   Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT   "In planta functional analysis and subcellular localization of the oomycete
RT   pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL   Front. Plant Sci. 9:286-286(2018).
CC   -!- FUNCTION: Secreted effector that acts as an elicitor that induces cell
CC       death in host plant cells. {ECO:0000269|PubMed:29706971}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host
CC       nucleus {ECO:0000269|PubMed:29706971}.
CC   -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC       cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC       phosphate. {ECO:0000305|PubMed:29706971}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CV40; -.
DR   SMR; P0CV40; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Host nucleus; Secreted; Signal; Virulence.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..477
FT                   /note="Secreted RxLR effector protein 102"
FT                   /id="PRO_0000447949"
FT   REGION          326..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          351..370
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          376..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          433..455
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           48..65
FT                   /note="RxLR-dEER"
FT                   /evidence="ECO:0000305|PubMed:29706971"
FT   COMPBIAS        326..341
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..455
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   477 AA;  53484 MW;  D6AE4FF6930DF74A CRC64;
     MRGGYYVLTA LFVVASSEIA AESGHQLQAN NHGRKIDDDA AMKSLSTRFL RESRGVHGNV
     ANEERSVYSV LAGMINEGIK KMPRTAEVLK RKSRVIDPSD KIPHEAKLVE EMFHAAKAKE
     TMESAEEYNE LKTATEDAEK ALKKHWNPSK TAVKGDDSHD IHSNEMLSVK NWWVDFTGLK
     STVVDDTQDD MVDSVHNAFV TVCDKNIKPT REETSFLSRL LNWKVANSPR SVHKQRLIQR
     AQRYVILDLW KMQNTCKVWP EWEKLSDTLK FSVLDYLLNL HYQRLVRMYN IFARKRPDRN
     PAPLNPELNL VGNTGTSAAM AVNKNSKGQI PYPSEPLNAA STSKGERFHL IKRSKRTSDG
     NTDIASLPSI RSKVRSSKSV MPLLTESTTS GDHSVPAKRS RFSSSGLSRA FSPYKPGDHT
     FITENSRLSF DGPRSAVDPY TQSKKHSTKA LAPSSTVFTP EDVDTKLSLG GIYDRST