ID   RL10A_DANRE             Reviewed;         216 AA.
AC   Q6PC69; Q6IQA0;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=60S ribosomal protein L10a;
GN   Name=rpl10a; ORFNames=zgc:73082;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P62906}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P62906}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P62906}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family.
CC       {ECO:0000305}.
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DR   EMBL; BC059454; AAH59454.1; -; mRNA.
DR   EMBL; BC071510; AAH71510.1; -; mRNA.
DR   RefSeq; NP_955930.1; NM_199636.1.
DR   AlphaFoldDB; Q6PC69; -.
DR   SMR; Q6PC69; -.
DR   STRING; 7955.ENSDARP00000062982; -.
DR   PaxDb; Q6PC69; -.
DR   PRIDE; Q6PC69; -.
DR   Ensembl; ENSDART00000062983; ENSDARP00000062982; ENSDARG00000042905.
DR   GeneID; 323305; -.
DR   KEGG; dre:323305; -.
DR   CTD; 4736; -.
DR   ZFIN; ZDB-GENE-030131-2025; rpl10a.
DR   eggNOG; KOG1570; Eukaryota.
DR   GeneTree; ENSGT00390000008767; -.
DR   HOGENOM; CLU_062853_3_0_1; -.
DR   InParanoid; Q6PC69; -.
DR   OMA; TMAINFL; -.
DR   OrthoDB; 1172076at2759; -.
DR   PhylomeDB; Q6PC69; -.
DR   TreeFam; TF300791; -.
DR   Reactome; R-DRE-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DRE-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-DRE-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DRE-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DRE-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DRE-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q6PC69; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 8.
DR   Bgee; ENSDARG00000042905; Expressed in pharyngeal gill and 23 other tissues.
DR   ExpressionAtlas; Q6PC69; baseline and differential.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0042541; P:hemoglobin biosynthetic process; IMP:ZFIN.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd00403; Ribosomal_L1; 1.
DR   Gene3D; 3.40.50.790; -; 1.
DR   InterPro; IPR002143; Ribosomal_L1.
DR   InterPro; IPR023674; Ribosomal_L1-like.
DR   InterPro; IPR028364; Ribosomal_L1/biogenesis.
DR   InterPro; IPR016095; Ribosomal_L1_3-a/b-sand.
DR   InterPro; IPR023673; Ribosomal_L1_CS.
DR   Pfam; PF00687; Ribosomal_L1; 1.
DR   PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR   SUPFAM; SSF56808; SSF56808; 1.
DR   PROSITE; PS01199; RIBOSOMAL_L1; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..216
FT                   /note="60S ribosomal protein L10a"
FT                   /id="PRO_0000125824"
FT   CONFLICT        61
FT                   /note="K -> Q (in Ref. 1; AAH71510)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   216 AA;  24622 MW;  A7495BCA5FE3DC0B CRC64;
     MSKVSRDTLY EAVKEVQAGS RRKKRKFLET VELQISLKNY DPQKDKRFSG TVRLKTTPRP
     KFSVCVLGDQ QHCDEAKAAE LPHMDIEALK KLNKNKKLVK KLAKKYDAFL ASESLIKQIP
     RILGPGLNKA GKFPSLLTHN ENLGTKVDEV KSTIKFQMKK VLCLAVAVGH VKMSEEELVY
     NIHLAVNFLV SLLKKNWQNV RALYIKSTMG KPQRLY