ID   RL10A_DICDI             Reviewed;         217 AA.
AC   Q86L05; Q550G5;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=60S ribosomal protein L10a;
GN   Name=rpl10a; ORFNames=DDB_G0276871;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [3]
RP   PROTEIN SEQUENCE OF 11-18; 79-90 AND 106-147, METHYLATION AT LYS-122, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RA   Bienvenut W.V., Veltman D.M., Insall R.H.;
RL   Submitted (JAN-2010) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL1 family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000019; EAL68937.1; -; Genomic_DNA.
DR   RefSeq; XP_642967.1; XM_637875.1.
DR   AlphaFoldDB; Q86L05; -.
DR   STRING; 44689.DDB0229949; -.
DR   PaxDb; Q86L05; -.
DR   PRIDE; Q86L05; -.
DR   EnsemblProtists; EAL68937; EAL68937; DDB_G0276871.
DR   GeneID; 8620839; -.
DR   KEGG; ddi:DDB_G0276871; -.
DR   dictyBase; DDB_G0276871; rpl10a.
DR   eggNOG; KOG1570; Eukaryota.
DR   HOGENOM; CLU_062853_3_0_1; -.
DR   InParanoid; Q86L05; -.
DR   OMA; TMAINFL; -.
DR   PhylomeDB; Q86L05; -.
DR   Reactome; R-DDI-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-DDI-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-DDI-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-DDI-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-DDI-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-DDI-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q86L05; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0000470; P:maturation of LSU-rRNA; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd00403; Ribosomal_L1; 1.
DR   Gene3D; 3.40.50.790; -; 1.
DR   InterPro; IPR002143; Ribosomal_L1.
DR   InterPro; IPR023674; Ribosomal_L1-like.
DR   InterPro; IPR028364; Ribosomal_L1/biogenesis.
DR   InterPro; IPR016095; Ribosomal_L1_3-a/b-sand.
DR   Pfam; PF00687; Ribosomal_L1; 1.
DR   PIRSF; PIRSF002155; Ribosomal_L1; 1.
DR   SUPFAM; SSF56808; SSF56808; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Methylation; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..217
FT                   /note="60S ribosomal protein L10a"
FT                   /id="PRO_0000326198"
FT   MOD_RES         122
FT                   /note="N6,N6-dimethyllysine; alternate"
FT                   /evidence="ECO:0000269|Ref.3"
FT   MOD_RES         122
FT                   /note="N6-methyllysine; alternate"
FT                   /evidence="ECO:0000269|Ref.3"
SQ   SEQUENCE   217 AA;  24340 MW;  7303AAD8DBC985A9 CRC64;
     MSKISSDQVR SIVSQLFKEA QESKRGFLET VELQINLKNY DTKKDKRFSG QIKIGTVTKP
     KLSVCVFADQ QHCDEATKIG AEFMDIEALK KIGPKNKKAI KKLSKKYDAF LASESILRQV
     PKLLGPGLNK VGKFPTLLTH SEDMASKIND VKSTVKFQLK KVLCLAVAVG HIELTEREVA
     TNIIQSINFL VSLLKKGWQN IKTLYVKTSM GPSHRVY