ID   RL10A_SCHPO             Reviewed;         221 AA.
AC   Q09127;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 144.
DE   RecName: Full=60S ribosomal protein L10-A;
DE   AltName: Full=QM protein homolog;
DE   AltName: Full=SpQM;
GN   Name=rpl1001; Synonyms=rpl10, rpl10a; ORFNames=SPBC18E5.04;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8621081; DOI=10.1016/0378-1119(95)00853-5;
RA   Masson J.-Y., Vadnais J., Ramotar D.;
RT   "The Schizosaccharomyces pombe spqM gene is a new member of the Qm
RT   transcription factor family.";
RL   Gene 170:153-154(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBUNIT: Component of the small ribosomal subunit. Mature ribosomes
CC       consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC       contains about 33 different proteins and 1 molecule of RNA (18S). The
CC       60S subunit contains about 49 different proteins and 3 molecules of RNA
CC       (25S, 5.8S and 5S) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- MISCELLANEOUS: There are two genes for L10 in S.pombe.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL16 family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Was originally thought to be a transcription factor that may
CC       bind Jun homologs such as GCN4 and YAP-1, and which may inhibit DNA
CC       binding and transactivation by Jun homologs.
CC       {ECO:0000305|PubMed:8621081}.
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DR   EMBL; U33214; AAB03806.1; -; mRNA.
DR   EMBL; CU329671; CAA22664.1; -; Genomic_DNA.
DR   PIR; JC4755; JC4755.
DR   RefSeq; NP_595850.1; NM_001021754.2.
DR   AlphaFoldDB; Q09127; -.
DR   SMR; Q09127; -.
DR   BioGRID; 277314; 2.
DR   STRING; 4896.SPBC18E5.04.1; -.
DR   iPTMnet; Q09127; -.
DR   MaxQB; Q09127; -.
DR   PaxDb; Q09127; -.
DR   PRIDE; Q09127; -.
DR   EnsemblFungi; SPBC18E5.04.1; SPBC18E5.04.1:pep; SPBC18E5.04.
DR   GeneID; 2540795; -.
DR   KEGG; spo:SPBC18E5.04; -.
DR   PomBase; SPBC18E5.04; rpl1001.
DR   VEuPathDB; FungiDB:SPBC18E5.04; -.
DR   eggNOG; KOG0857; Eukaryota.
DR   HOGENOM; CLU_084051_0_0_1; -.
DR   InParanoid; Q09127; -.
DR   OMA; HHVIREN; -.
DR   PhylomeDB; Q09127; -.
DR   Reactome; R-SPO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-SPO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-SPO-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-SPO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-SPO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-SPO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q09127; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISO:PomBase.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:PomBase.
DR   GO; GO:0002181; P:cytoplasmic translation; ISO:PomBase.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR   CDD; cd01433; Ribosomal_L16_L10e; 1.
DR   Gene3D; 3.90.1170.10; -; 1.
DR   InterPro; IPR001197; Ribosomal_L10e.
DR   InterPro; IPR016180; Ribosomal_L10e/L16.
DR   InterPro; IPR036920; Ribosomal_L10e/L16_sf.
DR   InterPro; IPR018255; Ribosomal_L10e_CS.
DR   PANTHER; PTHR11726; PTHR11726; 1.
DR   Pfam; PF00252; Ribosomal_L16; 1.
DR   PIRSF; PIRSF005590; Ribosomal_L10; 1.
DR   SUPFAM; SSF54686; SSF54686; 1.
DR   TIGRFAMs; TIGR00279; uL16_euk_arch; 1.
DR   PROSITE; PS01257; RIBOSOMAL_L10E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..221
FT                   /note="60S ribosomal protein L10-A"
FT                   /id="PRO_0000147127"
FT   CONFLICT        221
FT                   /note="A -> LRLTCNNEQCVN (in Ref. 1; AAB03806)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   221 AA;  25373 MW;  1014EA03C0EAAE88 CRC64;
     MARRPARCYR YCKNKPYPKS RYNRAVPDSK IRIFDLGRKR AGVDEFPLCI HLVSNEYEQI
     TSEALEAARI CANKYLVKIG GKDSFHLRVR AHPFHVVRIN KMLSCAGADR LQTGMRHAFG
     KPNGLVARVN IGQILMSVRT KDSSRATAIE ALRRCQYKFP GQQRIIVSKK WGFSQYARDE
     YIEKRSRGEI IPDGCYAKFL NKRGSLQEKL DLFPEASFNL A