ID   RL10L_BOVIN             Reviewed;         214 AA.
AC   Q2TBW8;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=60S ribosomal protein L10-like;
GN   Name=RPL10L;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Testis-specific component of the ribosome, which is required
CC       for the transition from prophase to metaphase in male meiosis I (By
CC       similarity). Compensates for the inactivated X-linked RPL10 paralog
CC       during spermatogenesis. The ribosome is a large ribonucleoprotein
CC       complex responsible for the synthesis of proteins in the cell. The
CC       small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and
CC       translates the encoded message by selecting cognate aminoacyl-transfer
CC       RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal
CC       catalytic site termed the peptidyl transferase center (PTC), which
CC       catalyzes the formation of peptide bonds, thereby polymerizing the
CC       amino acids delivered by tRNAs into a polypeptide chain. The nascent
CC       polypeptides leave the ribosome through a tunnel in the LSU and
CC       interact with protein factors that function in enzymatic processing,
CC       targeting, and the membrane insertion of nascent chains at the exit of
CC       the ribosomal tunnel (By similarity). {ECO:0000250|UniProtKB:P86048,
CC       ECO:0000250|UniProtKB:Q96L21}.
CC   -!- SUBUNIT: Component of the 60S large ribosomal subunit (LSU).
CC       {ECO:0000250|UniProtKB:Q96L21}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96L21}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL16 family.
CC       {ECO:0000305}.
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DR   EMBL; BC109561; AAI09562.1; -; mRNA.
DR   RefSeq; NP_001192330.1; NM_001205401.2.
DR   AlphaFoldDB; Q2TBW8; -.
DR   SMR; Q2TBW8; -.
DR   STRING; 9913.ENSBTAP00000007086; -.
DR   PaxDb; Q2TBW8; -.
DR   PeptideAtlas; Q2TBW8; -.
DR   PRIDE; Q2TBW8; -.
DR   Ensembl; ENSBTAT00000007086; ENSBTAP00000007086; ENSBTAG00000024582.
DR   GeneID; 538748; -.
DR   KEGG; bta:538748; -.
DR   CTD; 140801; -.
DR   VEuPathDB; HostDB:ENSBTAG00000024582; -.
DR   eggNOG; KOG0857; Eukaryota.
DR   GeneTree; ENSGT00390000003897; -.
DR   HOGENOM; CLU_084051_0_0_1; -.
DR   InParanoid; Q2TBW8; -.
DR   OMA; MSVRAKE; -.
DR   OrthoDB; 1215841at2759; -.
DR   TreeFam; TF300082; -.
DR   Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000009136; Chromosome 10.
DR   Bgee; ENSBTAG00000024582; Expressed in semen and 30 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0005840; C:ribosome; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007141; P:male meiosis I; ISS:UniProtKB.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd01433; Ribosomal_L16_L10e; 1.
DR   Gene3D; 3.90.1170.10; -; 1.
DR   InterPro; IPR001197; Ribosomal_L10e.
DR   InterPro; IPR016180; Ribosomal_L10e/L16.
DR   InterPro; IPR036920; Ribosomal_L10e/L16_sf.
DR   InterPro; IPR018255; Ribosomal_L10e_CS.
DR   PANTHER; PTHR11726; PTHR11726; 1.
DR   Pfam; PF00252; Ribosomal_L16; 1.
DR   PIRSF; PIRSF005590; Ribosomal_L10; 1.
DR   SUPFAM; SSF54686; SSF54686; 1.
DR   TIGRFAMs; TIGR00279; uL16_euk_arch; 1.
DR   PROSITE; PS01257; RIBOSOMAL_L10E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Differentiation; Meiosis; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Spermatogenesis.
FT   CHAIN           1..214
FT                   /note="60S ribosomal protein L10-like"
FT                   /id="PRO_0000283813"
SQ   SEQUENCE   214 AA;  24586 MW;  57C0CEC271316A3D CRC64;
     MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL
     SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG
     KPQGTVARVH IGQVIMSIRT KLQNKEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE
     FEDKVAKKRL IPDGCGVKYV PNRGPLDKWR ALHS