ID   RL10L_MACFA             Reviewed;         214 AA.
AC   Q4R4D3;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=60S ribosomal protein L10-like;
GN   Name=RPL10L; ORFNames=QtsA-10847;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Testis-specific component of the ribosome, which is required
CC       for the transition from prophase to metaphase in male meiosis I (By
CC       similarity). Compensates for the inactivated X-linked RPL10 paralog
CC       during spermatogenesis. The ribosome is a large ribonucleoprotein
CC       complex responsible for the synthesis of proteins in the cell. The
CC       small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and
CC       translates the encoded message by selecting cognate aminoacyl-transfer
CC       RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal
CC       catalytic site termed the peptidyl transferase center (PTC), which
CC       catalyzes the formation of peptide bonds, thereby polymerizing the
CC       amino acids delivered by tRNAs into a polypeptide chain. The nascent
CC       polypeptides leave the ribosome through a tunnel in the LSU and
CC       interact with protein factors that function in enzymatic processing,
CC       targeting, and the membrane insertion of nascent chains at the exit of
CC       the ribosomal tunnel (By similarity). {ECO:0000250|UniProtKB:P86048,
CC       ECO:0000250|UniProtKB:Q96L21}.
CC   -!- SUBUNIT: Component of the 60S large ribosomal subunit (LSU).
CC       {ECO:0000250|UniProtKB:Q96L21}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96L21}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL16 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB178981; BAE02032.1; -; mRNA.
DR   RefSeq; NP_001272159.1; NM_001285230.1.
DR   AlphaFoldDB; Q4R4D3; -.
DR   SMR; Q4R4D3; -.
DR   STRING; 9541.XP_005561240.1; -.
DR   Ensembl; ENSMFAT00000077259; ENSMFAP00000053587; ENSMFAG00000053210.
DR   GeneID; 101925609; -.
DR   CTD; 140801; -.
DR   eggNOG; KOG0857; Eukaryota.
DR   GeneTree; ENSGT00390000003897; -.
DR   OrthoDB; 1215841at2759; -.
DR   Proteomes; UP000233100; Chromosome 7.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0005844; C:polysome; IEA:Ensembl.
DR   GO; GO:0005840; C:ribosome; ISS:UniProtKB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR   GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR   GO; GO:0007141; P:male meiosis I; ISS:UniProtKB.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; ISS:UniProtKB.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd01433; Ribosomal_L16_L10e; 1.
DR   Gene3D; 3.90.1170.10; -; 1.
DR   InterPro; IPR001197; Ribosomal_L10e.
DR   InterPro; IPR016180; Ribosomal_L10e/L16.
DR   InterPro; IPR036920; Ribosomal_L10e/L16_sf.
DR   InterPro; IPR018255; Ribosomal_L10e_CS.
DR   PANTHER; PTHR11726; PTHR11726; 1.
DR   Pfam; PF00252; Ribosomal_L16; 1.
DR   PIRSF; PIRSF005590; Ribosomal_L10; 1.
DR   SUPFAM; SSF54686; SSF54686; 1.
DR   TIGRFAMs; TIGR00279; uL16_euk_arch; 1.
DR   PROSITE; PS01257; RIBOSOMAL_L10E; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Differentiation; Meiosis; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Spermatogenesis.
FT   CHAIN           1..214
FT                   /note="60S ribosomal protein L10-like"
FT                   /id="PRO_0000319305"
SQ   SEQUENCE   214 AA;  24617 MW;  BC6611FC8113BB6F CRC64;
     MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL
     SSEALEAARI CANKYMVKSC GRDGFHMRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG
     KPQGTVARVH IGQVIMSIRT KLQNKEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE
     FEDMVAKKRL IPDGCGVKYV PSHGPLDKWR VLHS