RL10_BOVIN
ID RL10_BOVIN Reviewed; 214 AA.
AC Q9XSI3; Q3MHY5; Q56JV2; Q5E939;
DT 27-APR-2001, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 4.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=60S ribosomal protein L10 {ECO:0000305};
DE AltName: Full=Protein QM homolog;
DE AltName: Full=Ribosomal protein L10 {ECO:0000250|UniProtKB:P27635};
GN Name=RPL10 {ECO:0000250|UniProtKB:P27635}; Synonyms=QM;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=10841175; DOI=10.1359/jbmr.2000.15.6.1066;
RA Green H., Canfield A.E., Hillarby M.C., Grant M.E., Boot-Handford R.P.,
RA Freemont A.J., Wallis G.A.;
RT "The ribosomal protein QM is expressed differentially during vertebrate
RT endochondral bone development.";
RL J. Bone Miner. Res. 15:1066-1075(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lymphoid epithelium;
RA Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT "Analysis of sequences obtained from constructed full-length bovine cDNA
RT libraries.";
RL Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Uterus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. Plays a role in the
CC formation of actively translating ribosomes. May play a role in the
CC embryonic brain development. {ECO:0000250|UniProtKB:P27635}.
CC -!- SUBUNIT: Component of the large ribosomal subunit. Mature ribosomes
CC consist of a small (40S) and a large (60S) subunit. The 40S subunit
CC contains about 33 different proteins and 1 molecule of RNA (18S). The
CC 60S subunit contains about 49 different proteins and 3 molecules of RNA
CC (28S, 5.8S and 5S). {ECO:0000250|UniProtKB:P27635}.
CC -!- PTM: Citrullinated by PADI4. {ECO:0000250|UniProtKB:Q6ZWV3}.
CC -!- PTM: Ufmylated by UFL1. {ECO:0000250|UniProtKB:Q6ZWV3}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL16 family.
CC {ECO:0000305}.
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DR EMBL; AF143815; AAD33912.1; -; mRNA.
DR EMBL; BT021081; AAX09098.1; -; mRNA.
DR EMBL; AY911380; AAW82143.1; -; mRNA.
DR EMBL; BC104528; AAI04529.1; -; mRNA.
DR RefSeq; NP_777185.1; NM_174760.2.
DR AlphaFoldDB; Q9XSI3; -.
DR SMR; Q9XSI3; -.
DR STRING; 9913.ENSBTAP00000009803; -.
DR PaxDb; Q9XSI3; -.
DR PRIDE; Q9XSI3; -.
DR Ensembl; ENSBTAT00000020266; ENSBTAP00000020266; ENSBTAG00000022275.
DR GeneID; 286790; -.
DR KEGG; bta:286790; -.
DR CTD; 6134; -.
DR VEuPathDB; HostDB:ENSBTAG00000022275; -.
DR eggNOG; KOG0857; Eukaryota.
DR GeneTree; ENSGT00390000003897; -.
DR HOGENOM; CLU_084051_0_0_1; -.
DR InParanoid; Q9XSI3; -.
DR OrthoDB; 1215841at2759; -.
DR TreeFam; TF300082; -.
DR Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR Proteomes; UP000009136; Chromosome 1.
DR Bgee; ENSBTAG00000022275; Expressed in theca cell and 104 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; ISS:UniProtKB.
DR GO; GO:0003735; F:structural constituent of ribosome; ISS:UniProtKB.
DR GO; GO:0045182; F:translation regulator activity; ISS:UniProtKB.
DR GO; GO:1990403; P:embryonic brain development; ISS:UniProtKB.
DR GO; GO:0006417; P:regulation of translation; ISS:UniProtKB.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd01433; Ribosomal_L16_L10e; 1.
DR Gene3D; 3.90.1170.10; -; 1.
DR InterPro; IPR001197; Ribosomal_L10e.
DR InterPro; IPR016180; Ribosomal_L10e/L16.
DR InterPro; IPR036920; Ribosomal_L10e/L16_sf.
DR InterPro; IPR018255; Ribosomal_L10e_CS.
DR PANTHER; PTHR11726; PTHR11726; 1.
DR Pfam; PF00252; Ribosomal_L16; 1.
DR PIRSF; PIRSF005590; Ribosomal_L10; 1.
DR SUPFAM; SSF54686; SSF54686; 1.
DR TIGRFAMs; TIGR00279; uL16_euk_arch; 1.
DR PROSITE; PS01257; RIBOSOMAL_L10E; 1.
PE 2: Evidence at transcript level;
KW Citrullination; Developmental protein; Isopeptide bond; Reference proteome;
KW Ribonucleoprotein; Ribosomal protein; Translation regulation;
KW Ubl conjugation.
FT CHAIN 1..214
FT /note="60S ribosomal protein L10"
FT /id="PRO_0000147104"
FT MOD_RES 32
FT /note="Citrulline"
FT /evidence="ECO:0000250|UniProtKB:Q6ZWV3"
FT CROSSLNK 175
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P27635"
FT CROSSLNK 188
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in ubiquitin)"
FT /evidence="ECO:0000250|UniProtKB:P27635"
FT CONFLICT 128
FT /note="R -> K (in Ref. 1; AAD33912)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 214 AA; 24603 MW; E6802ECC91DF74F4 CRC64;
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG HMVSDEYEQL
SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN KMLSCAGADR LQTGMRGAFG
KPQGTVARVH IGQVIMSIRT KLQNKEHVIE ALRRAKFKFP GRQKIHISKK WGFTKFNADE
FENMVAEKRL IPDGCGVKYI PNRGPLDKWR ALHS
