RL10_ECO57
ID RL10_ECO57 Reviewed; 165 AA.
AC P0A7J5; P02408;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=50S ribosomal protein L10;
GN Name=rplJ; OrderedLocusNames=Z5558, ECs4908;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- FUNCTION: Protein L10 is also a translational repressor protein. It
CC controls the translation of the rplJL-rpoBC operon by binding to its
CC mRNA (By similarity). {ECO:0000250}.
CC -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC the interaction of the ribosome with GTP-bound translation factors.
CC {ECO:0000250}.
CC -!- SUBUNIT: Part of the ribosomal stalk of the 50S ribosomal subunit. The
CC N-terminus interacts with L11 and the large rRNA to form the base of
CC the stalk. The C-terminus forms an elongated spine to which L12 dimers
CC bind in a sequential fashion forming a multimeric L10(L12)X complex (By
CC similarity). {ECO:0000250}.
CC -!- MISCELLANEOUS: Ribosomal protein L8 appears to be an aggregate of
CC ribosomal proteins L7/L12 and L10. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000305}.
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DR EMBL; AE005174; AAG59181.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB38331.1; -; Genomic_DNA.
DR PIR; A86090; A86090.
DR PIR; D91242; D91242.
DR RefSeq; NP_312935.1; NC_002695.1.
DR RefSeq; WP_001207201.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P0A7J5; -.
DR SMR; P0A7J5; -.
DR STRING; 155864.EDL933_5315; -.
DR EnsemblBacteria; AAG59181; AAG59181; Z5558.
DR EnsemblBacteria; BAB38331; BAB38331; ECs_4908.
DR GeneID; 67415314; -.
DR GeneID; 914951; -.
DR KEGG; ece:Z5558; -.
DR KEGG; ecs:ECs_4908; -.
DR PATRIC; fig|386585.9.peg.5132; -.
DR eggNOG; COG0244; Bacteria.
DR HOGENOM; CLU_092227_0_2_6; -.
DR OMA; VRDQKQA; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd05797; Ribosomal_L10; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR HAMAP; MF_00362; Ribosomal_L10; 1.
DR InterPro; IPR022973; Ribosomal_L10.
DR InterPro; IPR043141; Ribosomal_L10-like_sf.
DR InterPro; IPR002363; Ribosomal_L10_eubac_CS.
DR InterPro; IPR001790; Ribosomal_L10P.
DR PANTHER; PTHR11560; PTHR11560; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR SUPFAM; SSF160369; SSF160369; 1.
DR PROSITE; PS01109; RIBOSOMAL_L10; 1.
PE 3: Inferred from homology;
KW Acetylation; Reference proteome; Repressor; Ribonucleoprotein;
KW Ribosomal protein; RNA-binding; rRNA-binding; Translation regulation.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..165
FT /note="50S ribosomal protein L10"
FT /id="PRO_0000154628"
FT MOD_RES 37
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
FT MOD_RES 105
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 165 AA; 17712 MW; F15822B0EDB6AC02 CRC64;
MALNLQDKQA IVAEVSEVAK GALSAVVADS RGVTVDKMTE LRKAGREAGV YMRVVRNTLL
RRAVEGTPFE CLKDAFVGPT LIAYSMEHPG AAARLFKEFA KANAKFEVKA AAFEGELIPA
SQIDRLATLP TYEEAIARLM ATMKEASAGK LVRTLAAVRD AKEAA
