RL10_HALSA
ID RL10_HALSA Reviewed; 352 AA.
AC P13553; P17006; Q9HQL4;
DT 01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1990, sequence version 1.
DT 25-MAY-2022, entry version 130.
DE RecName: Full=50S ribosomal protein L10 {ECO:0000255|HAMAP-Rule:MF_00280};
DE AltName: Full=Acidic ribosomal protein P0 homolog {ECO:0000255|HAMAP-Rule:MF_00280};
DE AltName: Full=L10e;
GN Name=rpl10 {ECO:0000255|HAMAP-Rule:MF_00280};
GN Synonyms=rpl10p, rplP0 {ECO:0000255|HAMAP-Rule:MF_00280};
GN OrderedLocusNames=VNG_1104G;
OS Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS (Halobacterium halobium).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halobacterium.
OX NCBI_TaxID=64091;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=R1 / S9;
RX PubMed=2458258; DOI=10.1111/j.1432-1033.1988.tb14281.x;
RA Itoh T.;
RT "Complete nucleotide sequence of the ribosomal 'A' protein operon from the
RT archaebacterium, Halobacterium halobium.";
RL Eur. J. Biochem. 176:297-303(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 33170 / DSM 669 / NCCB 81095 / NRC 34001;
RX PubMed=2743981; DOI=10.1002/j.1460-2075.1989.tb03496.x;
RA Shimmin L.C., Dennis P.P.;
RT "Characterization of the L11, L1, L10 and L12 equivalent ribosomal protein
RT gene cluster of the halophilic archaebacterium Halobacterium cutirubrum.";
RL EMBO J. 8:1225-1235(1989).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX PubMed=11016950; DOI=10.1073/pnas.190337797;
RA Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA DasSarma S.;
RT "Genome sequence of Halobacterium species NRC-1.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC the interaction of the ribosome with GTP-bound translation factors.
CC {ECO:0000255|HAMAP-Rule:MF_00280}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms part of the ribosomal
CC stalk which helps the ribosome interact with GTP-bound translation
CC factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10
CC forms an elongated spine to which the L12 dimers bind in a sequential
CC fashion. {ECO:0000255|HAMAP-Rule:MF_00280}.
CC -!- MISCELLANEOUS: Was called L10e in this organism; in this case 'e' is
CC for E.coli-like, not eukaryotic-type protein.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000255|HAMAP-Rule:MF_00280}.
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DR EMBL; X13008; CAA31431.1; -; Genomic_DNA.
DR EMBL; X15078; CAA33180.1; -; Genomic_DNA.
DR EMBL; AE004437; AAG19499.1; -; Genomic_DNA.
DR PIR; G84266; G84266.
DR PIR; S01315; R5HSL0.
DR RefSeq; WP_010902794.1; NC_002607.1.
DR AlphaFoldDB; P13553; -.
DR SMR; P13553; -.
DR STRING; 64091.VNG_1104G; -.
DR PaxDb; P13553; -.
DR EnsemblBacteria; AAG19499; AAG19499; VNG_1104G.
DR GeneID; 5954214; -.
DR GeneID; 62886621; -.
DR KEGG; hal:VNG_1104G; -.
DR PATRIC; fig|64091.14.peg.845; -.
DR HOGENOM; CLU_053173_0_0_2; -.
DR InParanoid; P13553; -.
DR OMA; MAHVAEW; -.
DR OrthoDB; 73593at2157; -.
DR PhylomeDB; P13553; -.
DR Proteomes; UP000000554; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR Gene3D; 3.30.70.1730; -; 1.
DR Gene3D; 3.90.105.20; -; 1.
DR HAMAP; MF_00280; Ribosomal_L10_arch; 1.
DR InterPro; IPR022909; 50S_L10_arch.
DR InterPro; IPR043141; Ribosomal_L10-like_sf.
DR InterPro; IPR001790; Ribosomal_L10P.
DR InterPro; IPR043164; RL10_insert_sf.
DR InterPro; IPR040637; RL10P_insert.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR Pfam; PF17777; RL10P_insert; 1.
DR SUPFAM; SSF160369; SSF160369; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..352
FT /note="50S ribosomal protein L10"
FT /id="PRO_0000154790"
FT REGION 286..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..343
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 59
FT /note="L -> V (in Ref. 2; CAA33180)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 352 AA; 37213 MW; E2F088CF34FDB9BD CRC64;
MSAEEQRTTE EVPEWKRQEV AELVDLLETY DSVGVVNVTG IPSKQLQDMR RGLHGQAALR
MSRNTLLVRA LEEAGDGLDT LTEYVEGEVG LVATNDNPFG LYQQLENSKT PAPINAGEVA
PNDIVVPEGD TGIDPGPFVG ELQTIGANAR IQEGSIQVLD DSVVTEEGET VSDDVSNVLS
ELGIEPKEVG LDLRGVFSEG VLFTPEELEI DVDEYRADIQ SAAASARNLS VNAAYPTERT
APDLIAKGRG EAKSLGLQAS VESPDLADDL VSKADAQVRA LAAQIDDEDA LPEELQDVDA
PAAPAGGEAD TTADEQSDET QASEADDADD SDDDDDDDDG NAGAEGLGEM FG
