ID   RL10_METAC              Reviewed;         347 AA.
AC   Q8TI80;
DT   13-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=50S ribosomal protein L10 {ECO:0000255|HAMAP-Rule:MF_00280};
DE   AltName: Full=Acidic ribosomal protein P0 homolog {ECO:0000255|HAMAP-Rule:MF_00280};
GN   Name=rpl10 {ECO:0000255|HAMAP-Rule:MF_00280};
GN   Synonyms=rplP0 {ECO:0000255|HAMAP-Rule:MF_00280};
GN   OrderedLocusNames=MA_4276;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC       the interaction of the ribosome with GTP-bound translation factors.
CC       {ECO:0000255|HAMAP-Rule:MF_00280}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms part of the ribosomal
CC       stalk which helps the ribosome interact with GTP-bound translation
CC       factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10
CC       forms an elongated spine to which the L12 dimers bind in a sequential
CC       fashion. {ECO:0000255|HAMAP-Rule:MF_00280}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000255|HAMAP-Rule:MF_00280}.
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DR   EMBL; AE010299; AAM07620.1; -; Genomic_DNA.
DR   RefSeq; WP_011024157.1; NC_003552.1.
DR   AlphaFoldDB; Q8TI80; -.
DR   SMR; Q8TI80; -.
DR   STRING; 188937.MA_4276; -.
DR   PRIDE; Q8TI80; -.
DR   EnsemblBacteria; AAM07620; AAM07620; MA_4276.
DR   GeneID; 1476170; -.
DR   KEGG; mac:MA_4276; -.
DR   HOGENOM; CLU_053173_0_0_2; -.
DR   InParanoid; Q8TI80; -.
DR   OMA; MAHVAEW; -.
DR   OrthoDB; 73593at2157; -.
DR   PhylomeDB; Q8TI80; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IBA:GO_Central.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   HAMAP; MF_00280; Ribosomal_L10_arch; 1.
DR   InterPro; IPR022909; 50S_L10_arch.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..347
FT                   /note="50S ribosomal protein L10"
FT                   /id="PRO_0000154792"
FT   REGION          312..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        321..336
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   347 AA;  37167 MW;  359EEBDEDB28821F CRC64;
     MAEERHHTEH IPQWKKDEIE NIKELIQSHK VFGMVGIEGI LATKMQKIRR DLKDVAVLKV
     SRNTLTERAL NQLGETIPGM KEYLDKQTAL IFTNESPFKL YKLLEQTKTP SPIRGGAIAP
     ADITVQKGPT SFPPGPILGE LQSAGIPASI DAGKVAVKET KVVCKAGEVV PQKLATMLSK
     LEIYPLIVGL DLRAAYDDGT IYEPELLAVD ESKYFSDIIR AAQNAFNLSV NTAFPTSATI
     STLLAKASSE AKNLGVNAVI LEPGVMDTLL AKAHVQMTSV ASEAADKDAN AVDDDLREVL
     GAAASAAAAA AAAAPAEEEV KKEEEPEEEE EDHAEEDGMA GLGALFG