RL10_SALTY
ID RL10_SALTY Reviewed; 165 AA.
AC P0A297; P17352;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=50S ribosomal protein L10;
GN Name=rplJ; OrderedLocusNames=STM4151; ORFNames=STMF1.10;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=2187183; DOI=10.1093/nar/18.9.2824;
RA Paton E.B., Zolotukhin S.B., Woodmaska M.I., Kroupskaya I.V.,
RA Zhyvoloup A.N.;
RT "The nucleotide sequence of gene rpIJ encoding ribosomal protein L10 of
RT Salmonella typhimurium.";
RL Nucleic Acids Res. 18:2824-2824(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=2201953; DOI=10.1093/nar/18.15.4620;
RA Zhyvoloup A.N., Woodmaska M.I., Kroupskaya I.V., Paton E.B.;
RT "Nucleotide sequence of the rplJL operon and the deduced primary structure
RT of the encoded L10 and L7/L12 proteins of Salmonella typhimurium compared
RT to that of Escherichia coli.";
RL Nucleic Acids Res. 18:4620-4620(1990).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=2194828; DOI=10.1016/0014-5793(90)80901-t;
RA Paton E.B., Woodmaska M.I., Kroupskaya I.V., Zhyvoloup A.N., Matsuka G.K.;
RT "Evidence for the ability of L10 ribosomal proteins of Salmonella
RT typhimurium and Klebsiella pneumoniae to regulate rplJL gene expression in
RT Escherichia coli.";
RL FEBS Lett. 265:129-132(1990).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Protein L10 is also a translational repressor protein. It
CC controls the translation of the rplJL-rpoBC operon by binding to its
CC mRNA.
CC -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC the interaction of the ribosome with GTP-bound translation factors.
CC {ECO:0000250}.
CC -!- SUBUNIT: Part of the ribosomal stalk of the 50S ribosomal subunit. The
CC N-terminus interacts with L11 and the large rRNA to form the base of
CC the stalk. The C-terminus forms an elongated spine to which L12 dimers
CC bind in a sequential fashion forming a multimeric L10(L12)X complex (By
CC similarity). {ECO:0000250}.
CC -!- MISCELLANEOUS: Ribosomal protein L8 appears to be an aggregate of
CC ribosomal proteins L7/L12 and L10.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC {ECO:0000305}.
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DR EMBL; X17216; CAA35085.1; -; Genomic_DNA.
DR EMBL; X53072; CAA37245.1; -; Genomic_DNA.
DR EMBL; AF170176; AAF33497.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL22979.1; -; Genomic_DNA.
DR PIR; S10895; R5EB10.
DR RefSeq; NP_463020.1; NC_003197.2.
DR RefSeq; WP_001207203.1; NC_003197.2.
DR AlphaFoldDB; P0A297; -.
DR STRING; 99287.STM4151; -.
DR PaxDb; P0A297; -.
DR EnsemblBacteria; AAL22979; AAL22979; STM4151.
DR GeneID; 1255677; -.
DR GeneID; 64726278; -.
DR GeneID; 67460217; -.
DR KEGG; stm:STM4151; -.
DR PATRIC; fig|99287.12.peg.4363; -.
DR HOGENOM; CLU_092227_0_2_6; -.
DR OMA; VRDQKQA; -.
DR PhylomeDB; P0A297; -.
DR BioCyc; SENT99287:STM4151-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0015934; C:large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IBA:GO_Central.
DR CDD; cd05797; Ribosomal_L10; 1.
DR Gene3D; 3.30.70.1730; -; 1.
DR HAMAP; MF_00362; Ribosomal_L10; 1.
DR InterPro; IPR022973; Ribosomal_L10.
DR InterPro; IPR043141; Ribosomal_L10-like_sf.
DR InterPro; IPR002363; Ribosomal_L10_eubac_CS.
DR InterPro; IPR001790; Ribosomal_L10P.
DR PANTHER; PTHR11560; PTHR11560; 1.
DR Pfam; PF00466; Ribosomal_L10; 1.
DR SUPFAM; SSF160369; SSF160369; 1.
DR PROSITE; PS01109; RIBOSOMAL_L10; 1.
PE 3: Inferred from homology;
KW Reference proteome; Repressor; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding; Translation regulation.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..165
FT /note="50S ribosomal protein L10"
FT /id="PRO_0000154701"
SQ SEQUENCE 165 AA; 17801 MW; 678B166CE3C64642 CRC64;
MALNLQDKQA IVAEVSEVAK GALSAVVADS RGVTVDKMTE LRKAGREAGV YMRVVRNTLL
RRVVEGTQFE CLKDTFVGPT LIAYSMEHPG AAARLFKEFA KANAKFEVKA AAFEGELIPA
SQIDRLATLP TYEEAIARLM ATMKEASAGK LVRTLAAVRD AKEAA
