ID   RL117_PLAVT             Reviewed;         439 AA.
AC   P0CV47;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=Secreted RxLR effector protein 117 {ECO:0000303|PubMed:29706971};
DE   Flags: Precursor;
GN   Name=RXLR117 {ECO:0000303|PubMed:29706971};
OS   Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=143451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA   Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT   "In planta functional analysis and subcellular localization of the oomycete
RT   pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL   Front. Plant Sci. 9:286-286(2018).
CC   -!- FUNCTION: Secreted effector that acts as an elicitor that induces cell
CC       death in host plant cells. {ECO:0000269|PubMed:29706971}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host
CC       nucleus {ECO:0000269|PubMed:29706971}.
CC   -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC       cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC       phosphate. {ECO:0000305|PubMed:29706971}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CV47; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Host nucleus; Secreted; Signal; Virulence.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..439
FT                   /note="Secreted RxLR effector protein 117"
FT                   /id="PRO_0000447956"
FT   MOTIF           48..65
FT                   /note="RxLR-dEER"
FT                   /evidence="ECO:0000305|PubMed:29706971"
SQ   SEQUENCE   439 AA;  48608 MW;  C5BADC5DE389A582 CRC64;
     MRGAYYVLAA LLVVASSQIA AEFGHQLPVY DDGIMAARNA VVKTLPKRYL RGGHDVHDDS
     ANEERSLYSV LVSLINEGVM KLPRATEELN MMPRAADDVE VMFRPAEVNE EMPHITKEEL
     KKASKSAKEA LKKLWKPASR TAADGHASHD IPTGEKLYLD LEAWDIKEFH MRGGSVIKKH
     RSMIASVHQE FLNLCDPNLH PTAAETSLLW GMFHWKPELC TIEIHGRNLM RLAKRDVQKG
     VLKITSNELL DNQWNQLSDT HKLSVQNCLL NLYYQRWVRM YNIFKRNRPD LIAAPLNLEL
     NLGTSSALAL RKHSQVPSNA ASTSNVKSSV ITKRSKRTFD SNTGTISLSS KQAKMQSSKS
     VVPLLTGATT SGEHVVPMQN LKLSLGGPSG GFAPYEPPKA HSLKSLTPAS TALTLEDSET
     KLSLGGIYDK RTDKAPSVP