RL11_STRGR
ID RL11_STRGR Reviewed; 144 AA.
AC P36258; O32448;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=50S ribosomal protein L11 {ECO:0000255|HAMAP-Rule:MF_00736};
GN Name=rplK {ECO:0000255|HAMAP-Rule:MF_00736}; Synonyms=relC;
OS Streptomyces griseus.
OC Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC Streptomyces.
OX NCBI_TaxID=1911;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=N2-3-11;
RX PubMed=8039667; DOI=10.1111/j.1574-6968.1994.tb06863.x;
RA Kuberski S., Kasberg T., Distler J.;
RT "The nusG gene of Streptomyces griseus: cloning of the gene and analysis of
RT the A-factor binding properties of the gene product.";
RL FEMS Microbiol. Lett. 119:33-39(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 11984 / NBRC 13189 / SL-842;
RX PubMed=9323358; DOI=10.1007/s004380050528;
RA Kawamoto S., Zhang D., Ochi K.;
RT "Molecular analysis of the ribosomal L11 protein gene (rplK = relC) of
RT Streptomyces griseus and identification of a deletion allele.";
RL Mol. Gen. Genet. 255:549-560(1997).
CC -!- FUNCTION: Forms part of the ribosomal stalk which helps the ribosome
CC interact with GTP-bound translation factors. {ECO:0000255|HAMAP-
CC Rule:MF_00736}.
CC -!- SUBUNIT: Part of the ribosomal stalk of the 50S ribosomal subunit.
CC Interacts with L10 and the large rRNA to form the base of the stalk.
CC L10 forms an elongated spine to which L12 dimers bind in a sequential
CC fashion forming a multimeric L10(L12)X complex. {ECO:0000255|HAMAP-
CC Rule:MF_00736}.
CC -!- PTM: One or more lysine residues are methylated. {ECO:0000255|HAMAP-
CC Rule:MF_00736}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL11 family.
CC {ECO:0000255|HAMAP-Rule:MF_00736}.
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DR EMBL; X72787; CAA51297.1; -; Genomic_DNA.
DR EMBL; D87846; BAA22444.1; -; Genomic_DNA.
DR EMBL; D87846; BAA22445.1; -; Genomic_DNA.
DR PIR; S32235; S32235.
DR RefSeq; WP_003967000.1; NZ_UAVD01000027.1.
DR AlphaFoldDB; P36258; -.
DR SMR; P36258; -.
DR STRING; 1911.GCA_001715295_02336; -.
DR GeneID; 6209525; -.
DR OMA; CKQFNAK; -.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0070180; F:large ribosomal subunit rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00349; Ribosomal_L11; 1.
DR Gene3D; 1.10.10.250; -; 1.
DR Gene3D; 3.30.1550.10; -; 1.
DR HAMAP; MF_00736; Ribosomal_L11; 1.
DR InterPro; IPR000911; Ribosomal_L11/L12.
DR InterPro; IPR036796; Ribosomal_L11/L12_N_sf.
DR InterPro; IPR006519; Ribosomal_L11_bac-typ.
DR InterPro; IPR020783; Ribosomal_L11_C.
DR InterPro; IPR036769; Ribosomal_L11_C_sf.
DR InterPro; IPR020785; Ribosomal_L11_CS.
DR InterPro; IPR020784; Ribosomal_L11_N.
DR PANTHER; PTHR11661; PTHR11661; 1.
DR Pfam; PF00298; Ribosomal_L11; 1.
DR Pfam; PF03946; Ribosomal_L11_N; 1.
DR SMART; SM00649; RL11; 1.
DR SUPFAM; SSF46906; SSF46906; 1.
DR SUPFAM; SSF54747; SSF54747; 1.
DR TIGRFAMs; TIGR01632; L11_bact; 1.
DR PROSITE; PS00359; RIBOSOMAL_L11; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance; Methylation; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..144
FT /note="50S ribosomal protein L11"
FT /id="PRO_0000104380"
FT VARIANT 28..31
FT /note="Missing (in thiopeptin resistance)"
SQ SEQUENCE 144 AA; 15033 MW; D70E8D7FDCD68122 CRC64;
MPPKKKKVTG LIKLQINAGA ANPAPPVGPA LGQHGVNIME FCKAYNAATE SQRGMVVPVE
ITVYEDRSFT FVTKTPPAAK LILKAAGVDK GSGEPHKTKV AKLTAAQVRE IATTKLPDLN
ANDLDAASKI IAGTARSMGI TVEG
