ID   RL12_BOVIN              Reviewed;         165 AA.
AC   P61284; A5PJB1; Q3SZV1;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2004, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=60S ribosomal protein L12;
GN   Name=RPL12;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Shin M.L., Cui X.S., Park S.Y., Kim E.Y., Park S.P., Lee W.J., Hwang K.C.,
RA   Kim N.H.;
RT   "Analysis of gene expression in the bovine blastocyst or hatched blastocyst
RT   in vitro using ACP method.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal medulla, and Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds directly to 26S ribosomal RNA. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL11 family.
CC       {ECO:0000305}.
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DR   EMBL; AY528249; AAS20597.1; -; mRNA.
DR   EMBL; BC102693; AAI02694.1; -; mRNA.
DR   EMBL; BC142032; AAI42033.1; -; mRNA.
DR   RefSeq; NP_991366.1; NM_205797.1.
DR   AlphaFoldDB; P61284; -.
DR   SMR; P61284; -.
DR   STRING; 9913.ENSBTAP00000009152; -.
DR   PaxDb; P61284; -.
DR   PeptideAtlas; P61284; -.
DR   PRIDE; P61284; -.
DR   Ensembl; ENSBTAT00000009152; ENSBTAP00000009152; ENSBTAG00000006963.
DR   Ensembl; ENSBTAT00000009155; ENSBTAP00000009155; ENSBTAG00000025385.
DR   GeneID; 404133; -.
DR   KEGG; bta:404133; -.
DR   CTD; 6136; -.
DR   VEuPathDB; HostDB:ENSBTAG00000006963; -.
DR   VEuPathDB; HostDB:ENSBTAG00000025385; -.
DR   eggNOG; KOG0886; Eukaryota.
DR   GeneTree; ENSGT00390000006922; -.
DR   HOGENOM; CLU_074237_5_0_1; -.
DR   InParanoid; P61284; -.
DR   OMA; QPPHDVI; -.
DR   OrthoDB; 1279477at2759; -.
DR   TreeFam; TF300123; -.
DR   Reactome; R-BTA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-BTA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-BTA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-BTA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-BTA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   Proteomes; UP000009136; Chromosome 10.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000025385; Expressed in pharyngeal tonsil and 108 other tissues.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0015934; C:large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0070180; F:large ribosomal subunit rRNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   CDD; cd00349; Ribosomal_L11; 1.
DR   Gene3D; 1.10.10.250; -; 1.
DR   Gene3D; 3.30.1550.10; -; 1.
DR   HAMAP; MF_00736; Ribosomal_L11; 1.
DR   InterPro; IPR000911; Ribosomal_L11/L12.
DR   InterPro; IPR036796; Ribosomal_L11/L12_N_sf.
DR   InterPro; IPR020783; Ribosomal_L11_C.
DR   InterPro; IPR036769; Ribosomal_L11_C_sf.
DR   InterPro; IPR020785; Ribosomal_L11_CS.
DR   InterPro; IPR020784; Ribosomal_L11_N.
DR   PANTHER; PTHR11661; PTHR11661; 1.
DR   Pfam; PF00298; Ribosomal_L11; 1.
DR   Pfam; PF03946; Ribosomal_L11_N; 1.
DR   SMART; SM00649; RL11; 1.
DR   SUPFAM; SSF46906; SSF46906; 1.
DR   SUPFAM; SSF54747; SSF54747; 1.
DR   PROSITE; PS00359; RIBOSOMAL_L11; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Isopeptide bond; Phosphoprotein; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; RNA-binding; Ubl conjugation.
FT   CHAIN           1..165
FT                   /note="60S ribosomal protein L12"
FT                   /id="PRO_0000104454"
FT   MOD_RES         38
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P30050"
FT   MOD_RES         54
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P30050"
FT   MOD_RES         165
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P30050"
FT   CROSSLNK        40
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:P30050"
SQ   SEQUENCE   165 AA;  17819 MW;  7EFD783A8ED350F9 CRC64;
     MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT GDWKGLRITV
     KLTIQNRQAQ IEVVPSASAL IIKALKEPPR DRKKQKNIKH SGNITFDEIV NIARQMRHRS
     LARELSGTIK EILGTAQSVG CNVDGRHPHD IIDDINSGAV ECPAS