ID   RL12_HALMA              Reviewed;         115 AA.
AC   P15772; Q5V2A7;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=50S ribosomal protein L12 {ECO:0000255|HAMAP-Rule:MF_01478};
DE   AltName: Full=Hmal12;
GN   Name=rpl12 {ECO:0000255|HAMAP-Rule:MF_01478}; OrderedLocusNames=rrnAC1418;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2320419; DOI=10.1093/nar/18.5.1285;
RA   Arndt E., Weigel C.;
RT   "Nucleotide sequence of the genes encoding the L11, L1, L10 and L12
RT   equivalent ribosomal proteins from the archaebacterium Halobacterium
RT   marismortui.";
RL   Nucleic Acids Res. 18:1285-1285(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC       the interaction of the ribosome with GTP-bound translation factors.
CC       {ECO:0000305}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Homodimer, it forms part of
CC       the ribosomal stalk which helps the ribosome interact with GTP-bound
CC       translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex,
CC       where L10 forms an elongated spine to which the L12 dimers bind in a
CC       sequential fashion. {ECO:0000255|HAMAP-Rule:MF_01478}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01478}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X51430; CAA35796.1; -; Genomic_DNA.
DR   EMBL; AY596297; AAV46345.1; -; Genomic_DNA.
DR   PIR; S08423; R5HS12.
DR   RefSeq; WP_004957043.1; NZ_CP039138.1.
DR   AlphaFoldDB; P15772; -.
DR   SMR; P15772; -.
DR   IntAct; P15772; 1.
DR   STRING; 272569.rrnAC1418; -.
DR   EnsemblBacteria; AAV46345; AAV46345; rrnAC1418.
DR   GeneID; 40152385; -.
DR   GeneID; 64821979; -.
DR   KEGG; hma:rrnAC1418; -.
DR   PATRIC; fig|272569.17.peg.2112; -.
DR   eggNOG; arCOG04287; Archaea.
DR   HOGENOM; CLU_114656_2_0_2; -.
DR   OMA; EYIYAAM; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006414; P:translational elongation; IEA:InterPro.
DR   CDD; cd05832; Ribosomal_L12p; 1.
DR   Gene3D; 1.10.10.1410; -; 1.
DR   HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR   InterPro; IPR038716; P1/P2_N_sf.
DR   InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR   InterPro; IPR022295; Ribosomal_L12_arc.
DR   TIGRFAMs; TIGR03685; ribo_P1_arch; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..115
FT                   /note="50S ribosomal protein L12"
FT                   /id="PRO_0000157627"
FT   REGION          56..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..108
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   115 AA;  11773 MW;  F1B73268998E9DCC CRC64;
     MEYVYAALIL NEADEEINED NLTDVLDAAG VDVEESRVKA LVAALEDVDI EEAVDQAAAA
     PVPASGGAAA PAEGDADEAD EADEEAEEEA ADDGGDDDDD EDDEASGEGL GELFG