ID   RL12_HALVD              Reviewed;         113 AA.
AC   P41197; D4GWB6;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=50S ribosomal protein L12 {ECO:0000255|HAMAP-Rule:MF_01478};
GN   Name=rpl12 {ECO:0000255|HAMAP-Rule:MF_01478}; OrderedLocusNames=HVO_2755;
OS   Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS   NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=309800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2;
RX   PubMed=8755911; DOI=10.1128/jb.178.15.4737-4741.1996;
RA   Shimmin L.C., Dennis P.P.;
RT   "Conserved sequence elements involved in regulation of ribosomal protein
RT   gene expression in halophilic archaea.";
RL   J. Bacteriol. 178:4737-4741(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM
RC   B-1768 / DS2;
RX   PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA   Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA   Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA   Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT   "The complete genome sequence of Haloferax volcanii DS2, a model
RT   archaeon.";
RL   PLoS ONE 5:E9605-E9605(2010).
CC   -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC       the interaction of the ribosome with GTP-bound translation factors.
CC       {ECO:0000255|HAMAP-Rule:MF_01478}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Homodimer, it forms part of
CC       the ribosomal stalk which helps the ribosome interact with GTP-bound
CC       translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex,
CC       where L10 forms an elongated spine to which the L12 dimers bind in a
CC       sequential fashion. {ECO:0000255|HAMAP-Rule:MF_01478}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01478}.
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DR   EMBL; X58924; CAA41725.1; -; Genomic_DNA.
DR   EMBL; CP001956; ADE05052.1; -; Genomic_DNA.
DR   PIR; S34137; S34137.
DR   RefSeq; WP_004043001.1; NZ_AOHU01000047.1.
DR   AlphaFoldDB; P41197; -.
DR   SMR; P41197; -.
DR   STRING; 309800.C498_09064; -.
DR   EnsemblBacteria; ADE05052; ADE05052; HVO_2755.
DR   GeneID; 8924435; -.
DR   KEGG; hvo:HVO_2755; -.
DR   eggNOG; arCOG04287; Archaea.
DR   HOGENOM; CLU_114656_2_0_2; -.
DR   OMA; EYIYAAM; -.
DR   OrthoDB; 128352at2157; -.
DR   Proteomes; UP000008243; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006414; P:translational elongation; IEA:InterPro.
DR   Gene3D; 1.10.10.1410; -; 1.
DR   HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR   InterPro; IPR038716; P1/P2_N_sf.
DR   InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR   InterPro; IPR022295; Ribosomal_L12_arc.
DR   TIGRFAMs; TIGR03685; ribo_P1_arch; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein.
FT   CHAIN           1..113
FT                   /note="50S ribosomal protein L12"
FT                   /id="PRO_0000157629"
FT   REGION          56..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..106
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   113 AA;  11490 MW;  8A56170234394E01 CRC64;
     MEYVYAALIL NESDEEVNEE NITAVLEAAG VDVEESRVKA LVAALEDVDI EEAIETAAAA
     PAPAAGGSAG GEVEAADDDD EEDAEEEAAD EGGDDDGDDD EEADGEGLGA LFG