ID   RL12_METTH              Reviewed;         101 AA.
AC   P05394;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=50S ribosomal protein L12 {ECO:0000255|HAMAP-Rule:MF_01478};
DE   AltName: Full=Ribosomal protein 'A';
GN   Name=rpl12 {ECO:0000255|HAMAP-Rule:MF_01478}; OrderedLocusNames=MTH_1682;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-48.
RX   PubMed=7006702; DOI=10.1016/0005-2795(80)90207-x;
RA   Matheson A.T., Yaguchi M., Balch W.E., Wolfe R.S.;
RT   "Sequence homologies in the N-terminal region of the ribosomal 'A' proteins
RT   from Methanobacterium thermoautotrophicum and Halobacterium cutirubrum.";
RL   Biochim. Biophys. Acta 626:162-169(1980).
CC   -!- FUNCTION: Forms part of the ribosomal stalk, playing a central role in
CC       the interaction of the ribosome with GTP-bound translation factors.
CC       {ECO:0000255|HAMAP-Rule:MF_01478}.
CC   -!- SUBUNIT: Part of the 50S ribosomal subunit. Homodimer, it forms part of
CC       the ribosomal stalk which helps the ribosome interact with GTP-bound
CC       translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex,
CC       where L10 forms an elongated spine to which the L12 dimers bind in a
CC       sequential fashion. {ECO:0000255|HAMAP-Rule:MF_01478}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein P1/P2 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01478}.
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DR   EMBL; AE000666; AAB86154.1; -; Genomic_DNA.
DR   PIR; H69091; H69091.
DR   RefSeq; WP_010877289.1; NC_000916.1.
DR   AlphaFoldDB; P05394; -.
DR   SMR; P05394; -.
DR   STRING; 187420.MTH_1682; -.
DR   EnsemblBacteria; AAB86154; AAB86154; MTH_1682.
DR   GeneID; 1470767; -.
DR   KEGG; mth:MTH_1682; -.
DR   PATRIC; fig|187420.15.peg.1642; -.
DR   HOGENOM; CLU_114656_2_0_2; -.
DR   OMA; EYIYAAM; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006414; P:translational elongation; IEA:InterPro.
DR   CDD; cd05832; Ribosomal_L12p; 1.
DR   Gene3D; 1.10.10.1410; -; 1.
DR   HAMAP; MF_01478; Ribosomal_L12_arch; 1.
DR   InterPro; IPR038716; P1/P2_N_sf.
DR   InterPro; IPR027534; Ribosomal_L12/P1/P2.
DR   InterPro; IPR022295; Ribosomal_L12_arc.
DR   TIGRFAMs; TIGR03685; ribo_P1_arch; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..101
FT                   /note="50S ribosomal protein L12"
FT                   /id="PRO_0000157631"
FT   REGION          61..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..92
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   101 AA;  10480 MW;  6C1CEA3EF121FB85 CRC64;
     MEYIYAAMLL HTTGKEINEE NVKSVLEAAG AEVDDARVKA LIAALEDVDI EEAMETTAVA
     AAPAAAAAPA AAEEAEEEAE EEEEEEEAEE EAAAGLGALF G