AAPQ_RHIL3
ID AAPQ_RHIL3 Reviewed; 400 AA.
AC Q52813; Q1MH72;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=General L-amino acid transport system permease protein AapQ;
GN Name=aapQ; OrderedLocusNames=RL2203;
OS Rhizobium leguminosarum bv. viciae (strain 3841).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=216596;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8898392; DOI=10.1046/j.1365-2958.1996.00078.x;
RA Walshaw D.L., Poole P.S.;
RT "The general L-amino acid permease of Rhizobium leguminosarum is an ABC
RT uptake system that also influences efflux of solutes.";
RL Mol. Microbiol. 21:1239-1252(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3841;
RX PubMed=16640791; DOI=10.1186/gb-2006-7-4-r34;
RA Young J.P.W., Crossman L.C., Johnston A.W.B., Thomson N.R., Ghazoui Z.F.,
RA Hull K.H., Wexler M., Curson A.R.J., Todd J.D., Poole P.S., Mauchline T.H.,
RA East A.K., Quail M.A., Churcher C., Arrowsmith C., Cherevach I.,
RA Chillingworth T., Clarke K., Cronin A., Davis P., Fraser A., Hance Z.,
RA Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA Rabbinowitsch E., Sanders M., Simmonds M., Whitehead S., Parkhill J.;
RT "The genome of Rhizobium leguminosarum has recognizable core and accessory
RT components.";
RL Genome Biol. 7:R34.1-R34.20(2006).
CC -!- FUNCTION: Part of a binding-protein-dependent transport system for L-
CC amino acids, affects the uptake as well as efflux of these amino acids.
CC Probably responsible for the translocation of the substrate across the
CC membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. HisMQ subfamily. {ECO:0000305}.
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DR EMBL; X82596; CAA57934.1; -; Genomic_DNA.
DR EMBL; AM236080; CAK07695.1; -; Genomic_DNA.
DR RefSeq; WP_011651800.1; NC_008380.1.
DR AlphaFoldDB; Q52813; -.
DR STRING; 216596.RL2203; -.
DR TCDB; 3.A.1.3.8; the atp-binding cassette (abc) superfamily.
DR EnsemblBacteria; CAK07695; CAK07695; RL2203.
DR KEGG; rle:RL2203; -.
DR eggNOG; COG4597; Bacteria.
DR HOGENOM; CLU_019602_8_0_5; -.
DR OMA; ILFWYFA; -.
DR OrthoDB; 1523519at2; -.
DR Proteomes; UP000006575; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 2.
DR InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR InterPro; IPR043429; ArtM/GltK/GlnP/TcyL/YhdX-like.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR30614; PTHR30614; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 2.
DR TIGRFAMs; TIGR01726; HEQRo_perm_3TM; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..400
FT /note="General L-amino acid transport system permease
FT protein AapQ"
FT /id="PRO_0000059939"
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 96..388
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 400 AA; 43296 MW; F1DD1580E3EE287B CRC64;
MTHEAVDTTP LHGTGWSFRS AMYDPKYRSI FYQILTIVIL VGFVWWVAHN TAVNLARSNT
ASGFGFLRGR AGFEIGQSLI TFSSDSTYAR ALLVGILNTL LVAVTGIFTA TIIGFLIGIG
RLSRNWLIAK LCTVYVEVFR NIPPLLVIFF WYLGVLSVLP QPRESVGLPF SMYLNNRGLA
FPKPIFDTGM IAVGIALVIA IVASIIIARW AHKRQAATGQ PFHTVWTAIA LIVGLPLLVF
VVSGFPLTFD VPVAGKFNLT GGSVVGPEFM SLFLALSFYT ASFIAEIVRG GIRGVPKGQS
EAAGALGLHP SSVTRLVVVP QALRIIIPPL TSQYLNLTKN SSLAIAIGFS DLVAVGGTIL
NQSGQAIEIV CIWGIVYLSL SILTSLFMNW FNAKMALVER
