ID   AAPR1_AGRAE             Reviewed;         145 AA.
AC   O42717;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Aegerolysin Aa-Pri1;
DE   Flags: Precursor;
GN   Name=AA-PRI1;
OS   Agrocybe aegerita (Black poplar mushroom) (Agaricus aegerita).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Bolbitiaceae; Cyclocybe.
OX   NCBI_TaxID=1973307;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND DEVELOPMENTAL STAGE.
RC   STRAIN=SM 51; TISSUE=Mycelium;
RX   PubMed=9388298; DOI=10.1007/s002940050297;
RA   Fernandez-Espinar M.-T., Labarere J.;
RT   "Cloning and sequencing of the Aa-Pri1 gene specifically expressed during
RT   fruiting initiation in the edible mushroom Agrocybe aegerita, and analysis
RT   of the predicted amino-acid sequence.";
RL   Curr. Genet. 32:420-424(1997).
CC   -!- DEVELOPMENTAL STAGE: Expressed during fruiting initiation in primordia
CC       and immature fruiting bodies. {ECO:0000269|PubMed:9388298}.
CC   -!- SIMILARITY: Belongs to the aegerolysin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF004297; AAC02265.1; -; Genomic_DNA.
DR   AlphaFoldDB; O42717; -.
DR   SMR; O42717; -.
DR   TCDB; 1.C.119.1.1; the aegerolysin (aegerolysin) family.
DR   GO; GO:0019836; P:hemolysis by symbiont of host erythrocytes; IEA:InterPro.
DR   GO; GO:0044179; P:hemolysis in another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR009413; Aegerolysin-typ.
DR   Pfam; PF06355; Aegerolysin; 1.
DR   PIRSF; PIRSF007951; PIRSF007951; 1.
PE   2: Evidence at transcript level;
KW   Cytolysis; Hemolysis.
FT   PROPEP          1..8
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000000995"
FT   CHAIN           9..145
FT                   /note="Aegerolysin Aa-Pri1"
FT                   /id="PRO_0000000996"
SQ   SEQUENCE   145 AA;  16104 MW;  09EE4C169691EDDD CRC64;
     MDSNKDERAY AQWVIIILHN VGSSPFKIAN LGLSWGKLYA DGNKDKEVYP SDYNGKTVGP
     DEKIQINSCG RENASSGTEG SFDIVDPNDG NKTIRHFYWE CPWGSKRNTW TPSGSNTKWM
     VEWSGQNLDS GALGTITVDV LRKGN