RL14_PIG
ID RL14_PIG Reviewed; 213 AA.
AC A1XQU3;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=60S ribosomal protein L14;
GN Name=RPL14;
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Longissimus dorsi muscle;
RA Cai G., Chen Y., Wang C., Li J., Peng G., Zhang H.;
RT "Generation and analysis of cDNA sequences derived from a porcine skeletal
RT muscle library.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC large ribonucleoprotein complex responsible for the synthesis of
CC proteins in the cell. {ECO:0000250|UniProtKB:P50914}.
CC -!- SUBUNIT: Component of the large ribosomal subunit.
CC {ECO:0000250|UniProtKB:P50914}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P50914}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL14 family.
CC {ECO:0000305}.
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DR EMBL; DQ629165; ABK55649.1; -; mRNA.
DR RefSeq; NP_001090947.1; NM_001097478.1.
DR PDB; 3J7O; EM; 3.50 A; M=1-213.
DR PDB; 3J7P; EM; 3.50 A; M=1-213.
DR PDB; 3J7Q; EM; 3.50 A; M=1-213.
DR PDB; 3J7R; EM; 3.90 A; M=1-213.
DR PDBsum; 3J7O; -.
DR PDBsum; 3J7P; -.
DR PDBsum; 3J7Q; -.
DR PDBsum; 3J7R; -.
DR AlphaFoldDB; A1XQU3; -.
DR SMR; A1XQU3; -.
DR STRING; 9823.ENSSSCP00000012018; -.
DR PaxDb; A1XQU3; -.
DR PeptideAtlas; A1XQU3; -.
DR PRIDE; A1XQU3; -.
DR GeneID; 100037994; -.
DR KEGG; ssc:100037994; -.
DR CTD; 9045; -.
DR eggNOG; KOG3421; Eukaryota.
DR InParanoid; A1XQU3; -.
DR Proteomes; UP000008227; Unplaced.
DR Proteomes; UP000314985; Unplaced.
DR GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; IDA:UniProtKB.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0015934; C:large ribosomal subunit; IDA:UniProtKB.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd06088; KOW_RPL14; 1.
DR Gene3D; 2.30.30.30; -; 1.
DR InterPro; IPR014722; Rib_L2_dom2.
DR InterPro; IPR002784; Ribosomal_L14e_dom.
DR InterPro; IPR039660; Ribosomal_protein_L14.
DR InterPro; IPR041985; RPL14_KOW.
DR InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR PANTHER; PTHR11127; PTHR11127; 1.
DR Pfam; PF01929; Ribosomal_L14e; 1.
DR SUPFAM; SSF50104; SSF50104; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Cytoplasm; Isopeptide bond; Phosphoprotein;
KW Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein;
KW Ubl conjugation.
FT CHAIN 1..213
FT /note="60S ribosomal protein L14"
FT /id="PRO_0000289658"
FT REPEAT 169..173
FT /note="1-1; approximate"
FT REPEAT 174..178
FT /note="1-2"
FT REPEAT 179..183
FT /note="1-3"
FT REPEAT 184..188
FT /note="1-4"
FT REPEAT 191..193
FT /note="2-1"
FT REPEAT 194..196
FT /note="2-2"
FT REGION 166..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..188
FT /note="4 X 5 AA tandem repeats of Q-K-A-[APS]-X"
FT REGION 191..196
FT /note="2 X 3 AA tandem repeats of K-G-Q"
FT MOD_RES 79
FT /note="N6-acetyllysine"
FT /evidence="ECO:0000250|UniProtKB:P50914"
FT MOD_RES 85
FT /note="N6-acetyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:P50914"
FT MOD_RES 85
FT /note="N6-succinyllysine; alternate"
FT /evidence="ECO:0000250|UniProtKB:Q9CR57"
FT MOD_RES 139
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P50914"
FT MOD_RES 202
FT /note="N6-succinyllysine"
FT /evidence="ECO:0000250|UniProtKB:Q9CR57"
FT CROSSLNK 124
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:P50914"
SQ SEQUENCE 213 AA; 23330 MW; 33E71C1581616B65 CRC64;
MVFRRFVEVG RVAYVSFGPH AGKLVAIVDV IDQNRALVDG PCTQVRRQAM PFKCMQLTDF
ILKFPHSARQ KYVRKAWEKA DINAKWAATR WAKKIEAREK KAKMTDFDRY KVMKARKMRN
RLIKLEVKKL QKAALLKASP KKALAKGAAA AAAAAAAKVP VKKITTAGKK APAQKAPAQK
AAGQKAAPPP KAQKVQKPPA QKAPAPKASG EKA
