ID   RL14_RAT                Reviewed;         214 AA.
AC   Q63507;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=60S ribosomal protein L14;
GN   Name=Rpl14;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 2-41 AND 120-142.
RC   STRAIN=Sprague-Dawley; TISSUE=Liver;
RX   PubMed=8670222; DOI=10.1006/bbrc.1996.0761;
RA   Chan Y.-L., Olvera J., Wool I.G.;
RT   "The primary structure of rat ribosomal protein L14.";
RL   Biochem. Biophys. Res. Commun. 222:427-431(1996).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P50914}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P50914}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P50914}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL14 family.
CC       {ECO:0000305}.
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DR   EMBL; X94242; CAA63926.1; -; mRNA.
DR   PIR; JC4808; JC4808.
DR   AlphaFoldDB; Q63507; -.
DR   SMR; Q63507; -.
DR   IntAct; Q63507; 1.
DR   STRING; 10116.ENSRNOP00000061747; -.
DR   SwissPalm; Q63507; -.
DR   jPOST; Q63507; -.
DR   PaxDb; Q63507; -.
DR   PRIDE; Q63507; -.
DR   UCSC; RGD:621180; rat.
DR   RGD; 621180; Rpl14.
DR   eggNOG; KOG3421; Eukaryota.
DR   InParanoid; Q63507; -.
DR   Reactome; R-RNO-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-RNO-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-RNO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-RNO-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-RNO-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-RNO-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-RNO-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   PRO; PR:Q63507; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IDA:RGD.
DR   GO; GO:0022626; C:cytosolic ribosome; ISO:RGD.
DR   GO; GO:0014069; C:postsynaptic density; ISO:RGD.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:RGD.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; ISO:RGD.
DR   GO; GO:0006364; P:rRNA processing; ISO:RGD.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   CDD; cd06088; KOW_RPL14; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   InterPro; IPR014722; Rib_L2_dom2.
DR   InterPro; IPR002784; Ribosomal_L14e_dom.
DR   InterPro; IPR039660; Ribosomal_protein_L14.
DR   InterPro; IPR041985; RPL14_KOW.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR11127; PTHR11127; 1.
DR   Pfam; PF01929; Ribosomal_L14e; 1.
DR   SUPFAM; SSF50104; SSF50104; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Cytoplasm; Direct protein sequencing; Isopeptide bond;
KW   Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein;
KW   Ribosomal protein; Ubl conjugation.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:8670222"
FT   CHAIN           2..214
FT                   /note="60S ribosomal protein L14"
FT                   /id="PRO_0000132033"
FT   REPEAT          170..174
FT                   /note="1-1"
FT   REPEAT          175..179
FT                   /note="1-2"
FT   REPEAT          180..184
FT                   /note="1-3"
FT   REPEAT          185..189
FT                   /note="1-4"
FT   REPEAT          192..194
FT                   /note="2-1"
FT   REPEAT          195..197
FT                   /note="2-2"
FT   REGION          158..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          170..189
FT                   /note="4 X 5 AA tandem repeats of Q-K-A-[AS]-X"
FT   REGION          192..197
FT                   /note="2 X 3 AA tandem repeats of K-G-Q"
FT   MOD_RES         79
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P50914"
FT   MOD_RES         85
FT                   /note="N6-acetyllysine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:P50914"
FT   MOD_RES         85
FT                   /note="N6-succinyllysine; alternate"
FT                   /evidence="ECO:0000250|UniProtKB:Q9CR57"
FT   MOD_RES         139
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P50914"
FT   MOD_RES         203
FT                   /note="N6-succinyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9CR57"
FT   CROSSLNK        124
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:P50914"
SQ   SEQUENCE   214 AA;  23339 MW;  F16CAB6623E99C6F CRC64;
     MVFRRFVEVG RVAYISFGPH AGKLVAIVDV IDQNRALVDG PCTRVRRQAM PFKCMQLTDF
     ILKFPHSARQ KYVRKAWEKA DINTKWAATR WAKKIDARER KAKMTDFDRF KVMKAKKMRN
     RIIKTEVKKL QRAALLKASP KKAAVAKAAI AAAAAAKAKV PAKKATGPGQ KAAAQKASAQ
     KAAGQKAAPP AKGQKGQKTP AQKAPAPKAA GKKA