RL14_TREPA
ID RL14_TREPA Reviewed; 122 AA.
AC O83229;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 115.
DE RecName: Full=50S ribosomal protein L14 {ECO:0000255|HAMAP-Rule:MF_01367};
GN Name=rplN {ECO:0000255|HAMAP-Rule:MF_01367}; OrderedLocusNames=TP_0199;
OS Treponema pallidum (strain Nichols).
OC Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX NCBI_TaxID=243276;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nichols;
RX PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA Venter J.C.;
RT "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL Science 281:375-388(1998).
RN [2]
RP INTERACTION WITH RSFS.
RC STRAIN=Nichols;
RX PubMed=22829778; DOI=10.1371/journal.pgen.1002815;
RA Hauser R., Pech M., Kijek J., Yamamoto H., Titz B., Naeve F.,
RA Tovchigrechko A., Yamamoto K., Szaflarski W., Takeuchi N., Stellberger T.,
RA Diefenbacher M.E., Nierhaus K.H., Uetz P.;
RT "RsfA (YbeB) proteins are conserved ribosomal silencing factors.";
RL PLoS Genet. 8:E1002815-E1002815(2012).
CC -!- FUNCTION: Binds to 23S rRNA. Forms part of two intersubunit bridges in
CC the 70S ribosome. {ECO:0000255|HAMAP-Rule:MF_01367}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. Forms a cluster with
CC proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and
CC together make contacts with the 16S rRNA in bridges B5 and B8 (By
CC similarity). Interacts with ribosomal silencing factor RsfS, which may
CC inhibit ribosomal subunit association. {ECO:0000255|HAMAP-
CC Rule:MF_01367, ECO:0000269|PubMed:22829778}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL14 family.
CC {ECO:0000255|HAMAP-Rule:MF_01367}.
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DR EMBL; AE000520; AAC65184.1; -; Genomic_DNA.
DR PIR; A71356; A71356.
DR RefSeq; WP_010881646.1; NC_021490.2.
DR AlphaFoldDB; O83229; -.
DR SMR; O83229; -.
DR IntAct; O83229; 1.
DR STRING; 243276.TPANIC_0199; -.
DR EnsemblBacteria; AAC65184; AAC65184; TP_0199.
DR GeneID; 57878737; -.
DR KEGG; tpa:TP_0199; -.
DR eggNOG; COG0093; Bacteria.
DR HOGENOM; CLU_095071_2_1_12; -.
DR OMA; AKEVLCI; -.
DR OrthoDB; 1799923at2; -.
DR Proteomes; UP000000811; Chromosome.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.150.20; -; 1.
DR HAMAP; MF_01367; Ribosomal_L14; 1.
DR InterPro; IPR036853; Ribosomal_L14_sf.
DR InterPro; IPR000218; Ribosomal_L14P.
DR InterPro; IPR005745; Ribosomal_L14P_bac-type.
DR InterPro; IPR019972; Ribosomal_L14P_CS.
DR PANTHER; PTHR11761; PTHR11761; 1.
DR Pfam; PF00238; Ribosomal_L14; 1.
DR SMART; SM01374; Ribosomal_L14; 1.
DR SUPFAM; SSF50193; SSF50193; 1.
DR TIGRFAMs; TIGR01067; rplN_bact; 1.
DR PROSITE; PS00049; RIBOSOMAL_L14; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..122
FT /note="50S ribosomal protein L14"
FT /id="PRO_0000128568"
SQ SEQUENCE 122 AA; 13359 MW; 971E6D3DDA6ED85B CRC64;
MIQVQSRLNV ADNSGARLVQ CIKVVGGSRR RYASVGDIIV VAVKDALPTS VIKKGSVEKA
VIVRVSKEYR RVDGTYIRFD DNACVVIDAN GNPKGKRIFG PVARELRDMD FTKIVSLAPE
VL
