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ATPD_PROMO
ID   ATPD_PROMO              Reviewed;         174 AA.
AC   P29708;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=ATP synthase subunit delta, sodium ion specific {ECO:0000255|HAMAP-Rule:MF_01416};
DE   AltName: Full=ATP synthase F(1) sector subunit delta {ECO:0000255|HAMAP-Rule:MF_01416};
DE   AltName: Full=F-type ATPase subunit delta {ECO:0000255|HAMAP-Rule:MF_01416};
DE            Short=F-ATPase subunit delta {ECO:0000255|HAMAP-Rule:MF_01416};
GN   Name=atpH {ECO:0000255|HAMAP-Rule:MF_01416}; Synonyms=uncH;
OS   Propionigenium modestum.
OC   Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Propionigenium.
OX   NCBI_TaxID=2333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=DSM 2376 / Gra Succ2;
RX   PubMed=1533602; DOI=10.1016/0378-1097(92)90559-7;
RA   Krumholz L.R., Esser U., Simoni R.D.;
RT   "Characterization of the genes coding for the F1F0 subunits of the sodium
RT   dependent ATPase of Propionigenium modestum.";
RL   FEMS Microbiol. Lett. 70:37-41(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-118.
RC   STRAIN=DSM 2376 / Gra Succ2;
RX   PubMed=1386022; DOI=10.1111/j.1432-1033.1992.tb17072.x;
RA   Kaim G.W., Ludwig W., Dimroth P., Schleifer K.H.;
RT   "Cloning, sequencing and in vivo expression of genes encoding the F0 part
RT   of the sodium-ion-dependent ATP synthase of Propionigenium modestum in
RT   Escherichia coli.";
RL   Eur. J. Biochem. 207:463-470(1992).
RN   [3]
RP   PROTEIN SEQUENCE OF 1-7.
RX   PubMed=8422943; DOI=10.1016/0014-5793(93)81742-i;
RA   Gerike U., Dimroth P.;
RT   "N-terminal amino acid sequences of the subunits of the Na(+)-translocating
RT   F1F0 ATPase from Propionigenium modestum.";
RL   FEBS Lett. 316:89-92(1993).
CC   -!- FUNCTION: F(1)F(0) ATP synthase produces ATP from ADP in the presence
CC       of a proton or sodium gradient. F-type ATPases consist of two
CC       structural domains, F(1) containing the extramembraneous catalytic core
CC       and F(0) containing the membrane proton channel, linked together by a
CC       central stalk and a peripheral stalk. During catalysis, ATP synthesis
CC       in the catalytic domain of F(1) is coupled via a rotary mechanism of
CC       the central stalk subunits to proton translocation. {ECO:0000255|HAMAP-
CC       Rule:MF_01416}.
CC   -!- FUNCTION: This protein is part of the stalk that links CF(0) to CF(1).
CC       It either transmits conformational changes from CF(0) to CF(1) or is
CC       implicated in proton conduction. {ECO:0000255|HAMAP-Rule:MF_01416}.
CC   -!- SUBUNIT: F-type ATPases have 2 components, F(1) - the catalytic core
CC       - and F(0) - the membrane proton channel. F(1) has five subunits:
CC       alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main
CC       subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an
CC       alternating ring which encloses part of the gamma chain. F(1) is
CC       attached to F(0) by a central stalk formed by the gamma and epsilon
CC       chains, while a peripheral stalk is formed by the delta and b chains.
CC       {ECO:0000255|HAMAP-Rule:MF_01416}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01416}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01416}.
CC   -!- MISCELLANEOUS: The ATPase of P.modestum is of special interest because
CC       it uses sodium ions instead of protons as the physiological coupling
CC       ion.
CC   -!- SIMILARITY: Belongs to the ATPase delta chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01416}.
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DR   EMBL; X58461; CAA41371.1; -; Genomic_DNA.
DR   EMBL; X66102; CAA46897.1; -; Genomic_DNA.
DR   PIR; S29038; S29038.
DR   AlphaFoldDB; P29708; -.
DR   SMR; P29708; -.
DR   TCDB; 3.A.2.1.2; the h(+)- or na(+)-translocating f-type, v-type and a-type atpase (f-atpase) superfamily.
DR   PRIDE; P29708; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
DR   GO; GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:UniProtKB-UniRule.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.520.20; -; 1.
DR   HAMAP; MF_01416; ATP_synth_delta_bact; 1.
DR   InterPro; IPR026015; ATP_synth_OSCP/delta_N_sf.
DR   InterPro; IPR020781; ATPase_OSCP/d_CS.
DR   InterPro; IPR000711; ATPase_OSCP/dsu.
DR   PANTHER; PTHR11910; PTHR11910; 1.
DR   Pfam; PF00213; OSCP; 1.
DR   PRINTS; PR00125; ATPASEDELTA.
DR   SUPFAM; SSF47928; SSF47928; 1.
DR   TIGRFAMs; TIGR01145; ATP_synt_delta; 1.
DR   PROSITE; PS00389; ATPASE_DELTA; 1.
PE   1: Evidence at protein level;
KW   ATP synthesis; Cell inner membrane; Cell membrane; CF(1);
KW   Direct protein sequencing; Hydrogen ion transport; Ion transport; Membrane;
KW   Sodium; Sodium transport; Transport.
FT   CHAIN           1..174
FT                   /note="ATP synthase subunit delta, sodium ion specific"
FT                   /id="PRO_0000193474"
FT   CONFLICT        58..59
FT                   /note="KK -> FF (in Ref. 2; CAA46897)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        113..117
FT                   /note="FAIEP -> LRMNL (in Ref. 2; CAA46897)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   174 AA;  19945 MW;  94C1E8A60A311295 CRC64;
     MIEAQVGRRY AEAIYEIAES NDNVKELYET LNGVMELYNT DKEFKTLVDH PLIKREDKKE
     FAKKIFGELE ESSLNIIFYL IEKDRLSSIR GIVAEYLKIY YAKNQILDVE AIFAIEPTKD
     QKAKLIEQLE KKTGKKVNLE VSIDKSIIAG GIIKIGDEII DGSVRRQLDT IARS
 
 
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