RL15_MYCTU
ID RL15_MYCTU Reviewed; 146 AA.
AC P9WHD7; L0T7I9; P95071;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 03-AUG-2022, entry version 41.
DE RecName: Full=50S ribosomal protein L15 {ECO:0000255|HAMAP-Rule:MF_01341};
GN Name=rplO {ECO:0000255|HAMAP-Rule:MF_01341}; OrderedLocusNames=Rv0723;
GN ORFNames=MTCY210.42;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- FUNCTION: Binds to the 23S rRNA. {ECO:0000255|HAMAP-Rule:MF_01341}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01341}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL15 family.
CC {ECO:0000255|HAMAP-Rule:MF_01341}.
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DR EMBL; AL123456; CCP43467.1; -; Genomic_DNA.
DR PIR; F70644; F70644.
DR RefSeq; NP_215237.1; NC_000962.3.
DR RefSeq; WP_003898563.1; NZ_NVQJ01000007.1.
DR PDB; 5V7Q; EM; 3.70 A; L=1-146.
DR PDB; 7KGB; EM; 2.70 A; L=1-146.
DR PDB; 7MSC; EM; 2.97 A; L=1-146.
DR PDB; 7MSH; EM; 3.23 A; L=1-146.
DR PDB; 7MSM; EM; 2.79 A; L=1-146.
DR PDB; 7MSZ; EM; 3.10 A; L=1-146.
DR PDB; 7MT2; EM; 2.76 A; L=1-146.
DR PDB; 7MT3; EM; 2.80 A; L=1-146.
DR PDB; 7MT7; EM; 2.71 A; L=1-146.
DR PDBsum; 5V7Q; -.
DR PDBsum; 7KGB; -.
DR PDBsum; 7MSC; -.
DR PDBsum; 7MSH; -.
DR PDBsum; 7MSM; -.
DR PDBsum; 7MSZ; -.
DR PDBsum; 7MT2; -.
DR PDBsum; 7MT3; -.
DR PDBsum; 7MT7; -.
DR AlphaFoldDB; P9WHD7; -.
DR SMR; P9WHD7; -.
DR STRING; 83332.Rv0723; -.
DR PaxDb; P9WHD7; -.
DR DNASU; 888531; -.
DR GeneID; 888531; -.
DR KEGG; mtu:Rv0723; -.
DR TubercuList; Rv0723; -.
DR eggNOG; COG0200; Bacteria.
DR OMA; FKNINRV; -.
DR PhylomeDB; P9WHD7; -.
DR PRO; PR:P9WHD7; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01341; Ribosomal_L15; 1.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR030878; Ribosomal_L15.
DR InterPro; IPR005749; Ribosomal_L15_bac-type.
DR InterPro; IPR001196; Ribosomal_L15_CS.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR PANTHER; PTHR12934; PTHR12934; 1.
DR Pfam; PF00828; Ribosomal_L27A; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
DR TIGRFAMs; TIGR01071; rplO_bact; 1.
DR PROSITE; PS00475; RIBOSOMAL_L15; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..146
FT /note="50S ribosomal protein L15"
FT /id="PRO_0000104755"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 146 AA; 15533 MW; 60DF2C33340C2085 CRC64;
MTLKLHDLRP ARGSKIARTR VGRGDGSKGK TAGRGTKGTR ARKQVPVTFE GGQMPIHMRL
PKLKGFRNRF RTEYEIVNVG DINRLFPQGG AVGVDDLVAK GAVRKNALVK VLGDGKLTAK
VDVSAHKFSG SARAKITAAG GSATEL
