RL15_PYRFU
ID RL15_PYRFU Reviewed; 147 AA.
AC Q8U018;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=50S ribosomal protein L15 {ECO:0000255|HAMAP-Rule:MF_01341};
DE AltName: Full=Large ribosomal subunit protein uL15;
GN Name=rpl15 {ECO:0000255|HAMAP-Rule:MF_01341}; OrderedLocusNames=PF1802;
OS Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=186497;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA DiRuggiero J., Robb F.T.;
RT "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT horikoshii inferred from complete genomic sequences.";
RL Genetics 152:1299-1305(1999).
RN [2] {ECO:0007744|PDB:4V6U}
RP STRUCTURE BY ELECTRON MICROSCOPY (6.60 ANGSTROMS) IN THE 70S RIBOSOME, AND
RP SUBUNIT.
RX PubMed=23222135; DOI=10.1093/nar/gks1259;
RA Armache J.P., Anger A.M., Marquez V., Franckenberg S., Frohlich T.,
RA Villa E., Berninghausen O., Thomm M., Arnold G.J., Beckmann R.,
RA Wilson D.N.;
RT "Promiscuous behaviour of archaeal ribosomal proteins: implications for
RT eukaryotic ribosome evolution.";
RL Nucleic Acids Res. 41:1284-1293(2013).
CC -!- FUNCTION: Binds to the 23S rRNA. {ECO:0000255|HAMAP-Rule:MF_01341}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000255|HAMAP-
CC Rule:MF_01341, ECO:0000269|PubMed:23222135}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL15 family.
CC {ECO:0000255|HAMAP-Rule:MF_01341}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE009950; AAL81926.1; -; Genomic_DNA.
DR RefSeq; WP_011012943.1; NZ_CP023154.1.
DR PDB; 4V4N; EM; 9.00 A; L=1-147.
DR PDB; 4V6U; EM; 6.60 A; BL=1-147.
DR PDBsum; 4V4N; -.
DR PDBsum; 4V6U; -.
DR AlphaFoldDB; Q8U018; -.
DR SMR; Q8U018; -.
DR STRING; 186497.PF1802; -.
DR EnsemblBacteria; AAL81926; AAL81926; PF1802.
DR GeneID; 41713621; -.
DR KEGG; pfu:PF1802; -.
DR PATRIC; fig|186497.12.peg.1873; -.
DR eggNOG; arCOG00779; Archaea.
DR HOGENOM; CLU_109163_0_0_2; -.
DR OMA; WGRVGQH; -.
DR OrthoDB; 121171at2157; -.
DR PhylomeDB; Q8U018; -.
DR Proteomes; UP000001013; Chromosome.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 4.10.990.10; -; 1.
DR HAMAP; MF_01341; Ribosomal_L15; 1.
DR InterPro; IPR036227; L18e/L15P_sf.
DR InterPro; IPR027386; Rbsml_prot_L15/27a_N.
DR InterPro; IPR030878; Ribosomal_L15.
DR InterPro; IPR001196; Ribosomal_L15_CS.
DR InterPro; IPR021131; Ribosomal_L18e/L15P.
DR Pfam; PF00828; Ribosomal_L27A; 1.
DR SUPFAM; SSF52080; SSF52080; 1.
DR PROSITE; PS00475; RIBOSOMAL_L15; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome; Ribonucleoprotein; Ribosomal protein;
KW RNA-binding; rRNA-binding.
FT CHAIN 1..147
FT /note="50S ribosomal protein L15"
FT /id="PRO_0000104871"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..30
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 147 AA; 16400 MW; E86968E54BBBCE09 CRC64;
MIRRRKKVRK LRGSHTHGWG CKKKHRGGGS KGGRGMAGTG KRNKSKWTWT IKYAPDHLGK
RGFSRPPEVQ REVRVVNLKF IDEHLDELMQ MGIAYEEGGK IIVDVTQFAD KVLGTGKLTR
PLVIKARAFS PKAEEKIKAA GGEAVLV
