ID   RL160_PLAVT             Reviewed;         225 AA.
AC   P0CV71;
DT   18-SEP-2019, integrated into UniProtKB/Swiss-Prot.
DT   18-SEP-2019, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=Secreted RxLR effector protein 160 {ECO:0000303|PubMed:29706971};
DE   Flags: Precursor;
GN   Name=RXLR160 {ECO:0000303|PubMed:29706971};
OS   Plasmopara viticola (Downy mildew of grapevine) (Botrytis viticola).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Plasmopara.
OX   NCBI_TaxID=143451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=29706971; DOI=10.3389/fpls.2018.00286;
RA   Liu Y., Lan X., Song S., Yin L., Dry I.B., Qu J., Xiang J., Lu J.;
RT   "In planta functional analysis and subcellular localization of the oomycete
RT   pathogen Plasmopara viticola candidate RXLR effector repertoire.";
RL   Front. Plant Sci. 9:286-286(2018).
CC   -!- FUNCTION: Secreted effector that completely suppresses the host cell
CC       death induced by cell death-inducing proteins.
CC       {ECO:0000269|PubMed:29706971}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29706971}. Host cell
CC       {ECO:0000305|PubMed:29706971}. Membrane {ECO:0000255}; Single-pass type
CC       I membrane protein {ECO:0000255}.
CC   -!- DOMAIN: Has the canonical translocation RxLR motif, but lacks the
CC       canonical EER motif, which characterizes most oomycete effectors
CC       identified so far. {ECO:0000305|PubMed:29706971}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   AlphaFoldDB; P0CV71; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0043657; C:host cell; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Membrane; Secreted; Signal; Transmembrane; Transmembrane helix; Virulence.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..225
FT                   /note="Secreted RxLR effector protein 160"
FT                   /id="PRO_0000447981"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOTIF           77..80
FT                   /note="RxLR"
FT                   /evidence="ECO:0000305|PubMed:29706971"
SQ   SEQUENCE   225 AA;  25848 MW;  EA2BFE1FEB8F2D9C CRC64;
     MVFLLTALHL STFLLREMYQ IADIFEDHFA IVLFLWSLFL IPSVAVPFMS TRIARDGLLA
     FNVEHMKVAQ VIVQVSRLLR ARQTLRTLRF VAEMKIHLRE NVRRNNEQVM LNVEEKPQVP
     LPQAPRRRSS IIPIDATATF KAARRRSSTH LDPLVTAGVL RSIQQTPLPL PVASKATFEP
     PLSPLAAYLT PRKQRGDAYR REMERREIHT IFCLFDVDGS VCYSQ