RL17_CAEEL
ID RL17_CAEEL Reviewed; 187 AA.
AC Q9BL19; Q8WTK4;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=60S ribosomal protein L17;
GN Name=rpl-17; ORFNames=Y48G8AL.8;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a;
CC IsoId=Q9BL19-1; Sequence=Displayed;
CC Name=b;
CC IsoId=Q9BL19-2; Sequence=VSP_032019;
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC {ECO:0000305}.
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DR EMBL; FO081800; CCD73463.1; -; Genomic_DNA.
DR EMBL; FO081800; CCD73464.1; -; Genomic_DNA.
DR RefSeq; NP_740781.1; NM_170799.4. [Q9BL19-1]
DR AlphaFoldDB; Q9BL19; -.
DR SMR; Q9BL19; -.
DR BioGRID; 37191; 96.
DR DIP; DIP-26651N; -.
DR STRING; 6239.Y48G8AL.8a; -.
DR EPD; Q9BL19; -.
DR PaxDb; Q9BL19; -.
DR PeptideAtlas; Q9BL19; -.
DR EnsemblMetazoa; Y48G8AL.8.1; Y48G8AL.8.1; WBGene00004429. [Q9BL19-1]
DR GeneID; 171692; -.
DR KEGG; cel:CELE_Y48G8AL.8; -.
DR UCSC; Y48G8AL.8b; c. elegans. [Q9BL19-1]
DR CTD; 171692; -.
DR WormBase; Y48G8AL.8; CE22195; WBGene00004429; rpl-17. [Q9BL19-1]
DR eggNOG; KOG3353; Eukaryota.
DR GeneTree; ENSGT00950000183010; -.
DR HOGENOM; CLU_083987_0_1_1; -.
DR InParanoid; Q9BL19; -.
DR OMA; ANAEYKG; -.
DR OrthoDB; 1362349at2759; -.
DR PhylomeDB; Q9BL19; -.
DR Reactome; R-CEL-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR Reactome; R-CEL-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR Reactome; R-CEL-72689; Formation of a pool of free 40S subunits.
DR Reactome; R-CEL-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR Reactome; R-CEL-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR Reactome; R-CEL-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR PRO; PR:Q9BL19; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00004429; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR CDD; cd00336; Ribosomal_L22; 1.
DR Gene3D; 3.90.470.10; -; 1.
DR HAMAP; MF_01331_A; Ribosomal_L22_A; 1.
DR InterPro; IPR001063; Ribosomal_L22.
DR InterPro; IPR018260; Ribosomal_L22/L17_CS.
DR InterPro; IPR005721; Ribosomal_L22/L17_euk/arc.
DR InterPro; IPR036394; Ribosomal_L22/L17_sf.
DR PANTHER; PTHR11593; PTHR11593; 1.
DR Pfam; PF00237; Ribosomal_L22; 1.
DR SUPFAM; SSF54843; SSF54843; 1.
DR TIGRFAMs; TIGR01038; uL22_arch_euk; 1.
DR PROSITE; PS00464; RIBOSOMAL_L22; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome; Ribonucleoprotein;
KW Ribosomal protein.
FT CHAIN 1..187
FT /note="60S ribosomal protein L17"
FT /id="PRO_0000323400"
FT REGION 159..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 66..93
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_032019"
SQ SEQUENCE 187 AA; 21513 MW; 275B0781611075EA CRC64;
MTKVHYSRAP ENSTKSCKAR GSDLRVHFKN THEAAMALRG MPLRRAQAFL NHVKEHKEIV
PFRRFHGGIG RAAQTKQWNT TQGRWPVKSA DFLLDLLKNA ESNAEYKGLD VDHLVIEHIN
VQRAAKLRRR TYRAHGRINP YMSSPCHIEV ILAEKEDVVS KPTDDAAPKV KKESKRKQRR
QLARGEF